A Fundamental Breakthrough for Single-Cell Gene Expression Analysis
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The Fluidigm BioMark™ System revolutionizes how biologists can conduct single-cell gene expression experiments. Using microfluidic chips, the BioMark System features low input requirements and provides the sensitivity and assay throughput necessary for qPCR. Using standard TaqMan® and DNA binding dye assays, Fluidigm's proprietary Integrated Fluidic Circuit (IFC) technology enables single-cell discovery with the ability to screen hundreds of genes from single cells. Now with this unique technology it is possible to conduct up to 36,000 PCR reactions in one day, with one technician, and one BioMark System.
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Designed for gene expression studies and digital PCR, the BioMark System sets the new standard for high-throughput real-time qPCR assays, integrating thermal cycling and fluorescence detection on Digital Array™ IFCs and Dynamic Array™ IFCs.
Fluidigm technology is based on the Integrated Fluidic Circuit (IFC) systems that significantly improve productivity in life science research. Fluidigm's IFCs enable the simultaneous performance of PCR reactions in nanoliter volumes. These "integrated circuits for biology" are made possible by miniaturizing and integrating liquid handling components on a single microfluidic device. Fluidigm's systems, consisting of instrumentation, software and single-use chips, increase throughput, decrease costs and enhance sensitivity compared to conventional laboratory systems.
The BioMark System consists of a real-time PCR instrument, the Dynamic Array IFCs for multiplexing the samples and reagents, as well as an IFC loader to load the IFCs.
Fluidigm develops, manufactures and markets proprietary Integrated Fluidic Circuit (IFC) systems that significantly improve productivity in life science research. Fluidigm IFCs enable the simultaneous performance of thousands of sophisticated biochemical measurements in extremely minute volumes. These "integrated circuits for biology" are made possible by miniaturizing and integrating liquid handling components on a single microfluidic device. Fluidigm systems, consisting of instrumentation, software and chips, increase throughput, decrease costs and enhance sensitivity compared to conventional laboratory systems.