AMSBIO Introduces StemFit® for Differentiation of Human IPS and ES Cells
AMSBIO has introduced StemFit® for Differentiation – a new chemically defined and animal component-free formulation that aims to enable unmatched differentiation of human Induced Pluripotent Stem (hiPS) and Embryonic Stem (hES) cells.
The unique chemically defined composition of StemFit® for Differentiation minimizes lot-to-lot variation, enabling highly consistent cell differentiation. Free of animal- and human-derived components, StemFit® for Differentiation can be used to eliminate the risk of immunogenic contamination.
Applications proven to benefit from StemFit® for Differentiation include: lineage-specific (endodermal, mesodermal and ectodermal) differentiation where this new product is used to replace serum-free supplements, as well as spontaneous differentiation of hiPSCs to organoids via embryoid body formation.
Used in combination with StemFit Basic feeder-free medium with iMatrix-511 laminin as extracellular matrix, StemFit® for Differentiation enables researchers to undertake clinical applications involving both expansion and differentiation of human Pluripotent Stem Cell-derived cells and tissues.
Supplied as a 5X concentrate, StemFit® for Differentiation has been formulated for use with basal cell culture medium (e.g. DMEM, RPMI 1640, DMEM/F12 etc.) and a variety of different induction factors or cytokines (including Activin A and bFGF from AMSBIO).