Bispecific Antibody Binding Data to be Presented at PEGS 2012
Product News Mar 06, 2012
SAW Instruments will be exhibiting at this year’s PEGS protein engineering meeting in Boston, USA from 30 April until 4 May 2012.
SAW will showcase its new sam®X system (booth #12), which is optimized for more flexible and higher-throughput analysis.
SAW Instruments has also been collaborating with Affimed Therapeutics, with researchers using a sam® biosensor to investigate the binding of Affimed’s TandAb bispecific antibodies to malignant cancer cells.
Uwe Reusch, Ph.D., Head of Cell Culture at Affimed Therapeutics, will present data in his talk “High Affinity CD3 RECRUIT TandAbs for T Cell-Mediated Lysis of Malignant CD19+ B cells”, which is being held as part of the Antibody Stream (Wednesday 2nd May, 2.35pm) at the conference.
Dr Markus Perpeet, Managing Director of SAW Instruments, commented: “We are delighted that a customer of ours will share some of their latest high quality binding-affinity data, which is being generated with living cells using SAW’s innovative sam® biosensor systems. Our proprietary Surface Acoustic Wave (SAW) technology has significant advantages over traditional Surface Plasmon Resonance-based and other approaches, allowing users to generate real-time binding data using intact receptors on living cells, without having to worry about the unnatural effects caused by protein labelling, purification, solubilisation of receptors or fixing of cells.”
Dr Perpeet will be joined by a new recruit to the SAW team who is responsible for the role of Field Application Scientist for the US East Coast and has recently joined the company as part of its continued expansion into the US market.
As well as offering in-depth information on the applications and capabilities of the sam® range of systems, the team will be providing on-booth, personal user demonstrations of the sam®X.
The new system features eight sensor channels and adaptable microfluidic routing, providing a flexible, higher-throughput option for studying binding events and protein conformational changes.
Demonstration slots can be pre-booked at the contact page on the SAW website.
Within the next month, SAW will also be announcing news of an exciting new customer promotion for the sam®X, full details of which can be found by visiting the company’s booth at PEGS 2012.