We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Caliber I.D. to Debut  New Class Of Confocal Microscope
Product News

Caliber I.D. to Debut New Class Of Confocal Microscope

Caliber I.D. to Debut  New Class Of Confocal Microscope
Product News

Caliber I.D. to Debut New Class Of Confocal Microscope


Want a FREE PDF version of This Product News?

Complete the form below and we will email you a PDF version of "Caliber I.D. to Debut New Class Of Confocal Microscope"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

Caliber I.D. launches the RS-G4, a new class of modular confocal microscope that delivers confocal’s expected high resolution and clean contrast while overcoming its limited scan areas. Scanning large areas at lightning fast speeds, RS-G4 dramatically cuts the time required for efficient study of next-generation large format samples including brain slices, plant cross-sections, or large fields of cells or tissue critical for high-throughput screening. 

Consider the attached image of a whole mouse brain (Figure 1).  The RS-G4 scanned and stitched 1050 fields to image this 12mm x 8mm area (approximately 0.5” x 0.25”) in just 270 seconds (4.5 minutes), approximately one-tenth the time required by other currently-available systems.  Yet, as demonstrated by the inset, the image retains all the confocal detail and resolution offered by the 40x/1.30NA oil immersion objective. 

The cornerstone of RS-G4’s innovative performance is its high-speed strip mosaic imaging. On the hardware side, continual stage movement is coordinated with the resonant scanning of the confocal microscope.  Simultaneously, a proprietary stitching algorithm assembles and aligns mosaic strips with pixel level resolution. Hardware and software control are integrated under an easy-to-use, intuitive GUI.  Adding a new laser launch opens opportunities for fluorescence excitation at 405nm, 488nm, 561nm, 640nm and, critical for deep tissue neuroscience, 785 nm.  In addition, the RS-G4 can collect large area 3D image stacks that can be readily imported by any conventional processing package such as Image J or Imaris.  Surprisingly, all of this capability comes in a small 18” x 15” footprint.      

“We at Caliber are thrilled to be launching this revolutionary product (the RS-G4) into the research market,” said Robert Kelley, Caliber I.D.’s Vice President of Sales.  “For researchers, this increased scan speed means greater productivity and shorter time to publication.”  

Caliber I.D.’s RS-G4 with the new multi-laser launch will be running samples in BOOTH# 130 at the annual meeting of the Society for Neuroscience, November 12-16, in San Diego, CA.

Advertisement