
Product News
First Ready-To-Use, Synthetic Surface Cultureware for iPSCs and MSCs Available

Product News
First Ready-To-Use, Synthetic Surface Cultureware for iPSCs and MSCs Available
CCCadvanced™ FN 1 motifs cell cultureware
Want a FREE PDF version of This Product News?
Complete the form below and we will email you a PDF version of "First Ready-To-Use, Synthetic Surface Cultureware for iPSCs and MSCs Available"
First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?
Biological coatings to expand stem cells are inherently complex and non-defined growth surfaces that frequently reduce experimental reproducibility. This is exacerbated by lot-to-lot variations of coating media, by use of undefined growth factors and extracellular matrix (ECM) components known to sustain cell adhesion and pluripotency, as well as by a potential pathogen contamination risk during preparation and storage. Therefore, to provide defined conditions fully synthetic, animal-/human-component-free culture systems are of great interest.
However, in contrast to other types of stem cells, synthetic and ready-to-use growth surfaces are currently not available for human induced PSCs (hiPSCs). Eppendorf now introduced a ready-to-use surface with synthetic fibronectin-derived motifs to support cell attachment by mimicking native ECM proteins. According to the manufacturer, this novel surface supports long-term expansion of hiPSCs over 25 passages and is also suitable for hMSCs and other ECM-dependent cells. Furthermore, it allows expansion of stem cells in xeno-free and restrictive culture conditions, aiming to provide a completely defined culture system for PSCs without animal or human components.
However, in contrast to other types of stem cells, synthetic and ready-to-use growth surfaces are currently not available for human induced PSCs (hiPSCs). Eppendorf now introduced a ready-to-use surface with synthetic fibronectin-derived motifs to support cell attachment by mimicking native ECM proteins. According to the manufacturer, this novel surface supports long-term expansion of hiPSCs over 25 passages and is also suitable for hMSCs and other ECM-dependent cells. Furthermore, it allows expansion of stem cells in xeno-free and restrictive culture conditions, aiming to provide a completely defined culture system for PSCs without animal or human components.
Advertisement