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Hepregen Launches First Dog HepatoPac® Assay Kit

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Hepregen Corporation has announced the commercial launch of the company's first dog HepatoPac® kit designed specifically for metabolite identification and profiling applications. Each kit contains one or more standard 24-well tissue culture plates featuring uniquely configured micro-patterned dog liver cells co-cultured with specially selected stromal cells that support the highest level of performance observed in Hepregen's micro-patterned co-culture platform.

The dog liver cells (hepatocytes) on these plates mirror the behavior of liver cells in live animals, enabling scientists to generate data that can be useful for evaluation of the metabolism of chemical agents, including drug candidates, improving the design of preclinical experiments.

The remarkable flexibility of Hepregen's micro-patterned HepatoPac® platform allowed Hepregen scientists to develop a dog product that provides investigators with uniquely stable canine hepatocytes. The tissue culture maintains functionality and morphology for weeks, enabling experiments not previously possible.

Dr. Vincent Zurawski, Hepregen's Chief Executive Officer stated, "This new dog product provides another HepatoPac® application-directed kit serving the drug- and chemical-metabolism market. The unprecedented performance of the kit is enabled by a proprietary species-specific set of features that may be adaptable to all live-cell, in vitro products that contain primary dog hepatocytes. The introduction of our dog kit provides customers with a complete set of products relevant to drug development: human, monkey, rat and now dog HepatoPac® kits for metabolite identification and profiling."