Lonza’s Rapid PyroCell® Monocyte Activation Test Systems Make Rabbit-Free Pyrogen Testing Faster, Easier, and More Efficient
Complete the form below to unlock access to ALL audio articles.
Lonza has launched two new rapid monocyte activation test (MAT) systems, the PyroCell® MAT Rapid System and PyroCell® MAT Human Serum (HS) Rapid System, to streamline and simplify rabbit-free pyrogen testing. The systems, which will replace Lonza’s current MAT system kit offerings, contain the new PeliKine Human IL-6 Rapid ELISA Kit that minimizes hands-on time and reduces time-to-results from two days to two hours. The new tests give pharma manufacturers easier, faster, and more efficient MAT testing options for product safety testing while helping to reduce the reliance on animals.
Historically, pyrogen testing of pharmaceuticals has relied on the Rabbit Pyrogen Test (RPT), an unsustainable method requiring significant time-to-results. Pharma manufacturers now face growing pressure to discontinue the RPT due to ethical concerns, regulatory initiatives, and directives to increase the efficiency of QC pyrogen testing programs.
Orla Cloak, VP, Head of Bioprocessing Solutions, Lonza, commented: “With the RPT set to be discontinued in Europe by 2026, and sustainability a growing focus, pharmaceutical manufacturers are looking to adopt an RPT replacement. We’ve leveraged our long collaboration with Essange Reagents, formerly Sanquin Reagents, to deliver the new PyroCell® MAT Rapid Systems, offering customers two MAT solutions that are easier to execute. Transitioning to rabbit-free, sustainable pyrogen testing has never been simpler.”
Lonza will discontinue its current PyroCell® MAT System and PyroCell® MAT Human Serum (HS) System by early 2024.