CellCelector Flex – High-Throughput Image-Based Single-Cell Cloning
High-throughput nanowell-based image-verified cloning technology (HT-NIC) is a new method allowing the fast generation of clonal pharmaceutical production cell lines. Clones are generated in just one cloning round while providing robust in-process image-verified monoclonality proof.
Due to this integrated monoclonality and viability assessment of clones, as well as industry-leading outgrowth rates after clone transfer into 96- or 384-well plates, the CellCelector Flex single cell cloning technology represents the next generation of single cell cloning approaches. It goes far beyond the traditional methods and provides a superior alternative to limiting dilution (LD), fluorescence-activated cell sorting (FACS), or single cell printing techniques. This patent-pending method has been developed and validated in collaboration with ProBioGen AG and other CellCelector Flex customers.