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Tfh Cells and Associated Cytokines: The B Cell Modulators

Tfh Cells and Associated Cytokines: The B Cell Modulators


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The T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells essential for the survival, affinity maturation, and class switch recombination of B cells. They promote effective B-cell antibody-mediated immune responses. Dysregulation of Tfh cells is linked to autoimmune disorder systemic sclerosis and chronic graft-versus-host-disease. These cells also play essential roles in allergies, asthma, viral infections, and cancer. There is a growing interest in utilizing these cells to improve therapeutic and vaccination strategies.

Several prominent cytokines positively or negatively regulate Tfh cell differentiation and development. Sino Biological has developed a comprehensive collection of high-quality cytokines that support the research in the development and applications of Tfh cells.


About Sino Biological Inc
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offers pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates