Cell Culture – News and Features

News
New Gene Editor Enables Greater Precision
Scientists have developed an advanced gene editor – the evoCAST – that can add long stretches of DNA to defined locations in the human genome without creating unwanted modifications.

News
Bioprinted Organoids Capture Tumor Features and Predict Prognosis
Researchers have created a groundbreaking 3D-printed artificial tumor tissue capable of replicating the in vivo conditions of patient-derived cancer cells, which can be used to predict prognosis.

News
Genome of Extinct Rhino Male Becomes Blueprint for Restoration
Researchers have completed the full genome of the northern white rhinoceros, aiding efforts to rescue the functionally extinct species. The high-quality reference genome enables quality control of stem cells intended to create sperm and eggs.

News
Interplay Between STAT3 and STAT5 May Unlock Better Immunotherapy Outcomes
Researchers have identified that the balance between two proteins – STAT3 and STAT5 – is important for making tumors vulnerable to immune checkpoint therapy and targeting STAT3 degradation is a potential novel cancer immunotherapy strategy.

News
Nasal Spray Antibody Treatment Protects Mice From Flu
Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The protective effect was enhanced by delivering the antibody in a nasal spray.

News
AI-Engineered DNA Turns Genes On and Off in Blood Cells
A new study shows AI can design synthetic DNA to precisely control gene expression in healthy mammalian cells. The model created custom enhancers from scratch, enabling selective gene activation or suppression in blood cell types.

News
Scientists Develop Precision Tool for Mitochondrial DNA Manipulation
Researchers have developed a new precision tool for manipulating mitochondrial DNA. The method shows potential for improving research models and as a potential therapeutic strategy for treating mitochondrial diseases.

Article
Building Living Therapeutics With Synthetic Biology
This article explores how synthetic biology is revolutionizing therapeutics through engineered cells, precision genetic circuits and AI-driven design, with applications in cancer treatment, vaccine development and next-generation immunotherapies.

News
Injectable Polymer Could Prevent Heart Failure After a Heart Attack
Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The injectable protein-like polymer intervenes in the body’s response to stress and inflammation.

Industry Insight
Presenting a Universal Cell Engineering Solution
Portal Bio’s microfluidic technology enhances drug discovery and cell engineering by enabling efficient, scalable molecular delivery for sensitive cell types.
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