Cell Culture – News and Features

Scientists have identified a promising new drug target for acute myeloid leukemia, a deadly blood cancer with a five-year survival rate of just 30%, highlighting the crucial role of a protein called paraspeckle component 1.

Researchers have found that an FDA-approved arthritis drug suppresses seizures and improves memory, offering new hope for a potential epilepsy treatment.

The complexity of the TME in vivo limits the conclusions that can be drawn from in vivo models. Optimizing cell culture models to mimic the TME is vital to understanding cancer progression and the development of optimized therapies.

New research shows that glucose regulates tissue differentiation by binding to hundreds of proteins throughout the cell to modulate their function and promote differentiation.

Recent studies have discovered microplastics inside human organs, the brain and the blood. But does this accumulation of plastic have any adverse effect on our health? Experts suggest that more research is still needed.

Endometrial organoids, 3D cell cultures mimicking the endometrium, offer new opportunities in endometriosis research. These models are key in studying drug targets, fertility issues and gynecological cancers.

New research has provided insight into the biological mechanisms that may contribute to poor outcomes in certain cases of neuroblastoma – a cancer that develops in nerve tissue and primarily affects children.

A study reveals mitochondrial dysfunction in lymphoblast cell lines (LCLs) from children with Dravet syndrome. These cells exhibited reduced energy production, providing insights into the condition’s neurological symptoms.

ETH researchers discovered related structures in Asgard archaea and describe their structure. These experiments show that Asgard tubulins form very similar microtubules, albeit smaller than those in their eukaryotic relatives.

One of the key challenges of the modern genomics era is studying the thousands of genes in a single human cell at scale. To overcome this, scientists have developed PERISCOPE, which combines the power of microscopy imaging with CRISPR screening.