Cell Culture – News and Features

A specialist in flow cytometry, cell sorting and cellular biology, Dr. Richard Cuthbert shared his perspectives on the current and future applications of flow cytometry – and automated flow cytometry systems – in modern drug discovery.

Scientists from the University of Cologne identified the 1N4R tau isoform as a key contributor to neuronal dysfunction in Alzheimer’s. They found that this tau variant increases vulnerability to amyloid beta and phosphorylated tau aggregates.

Researchers at Rice University and Vanderbilt University found that combining focused ultrasound (FUS) with TRAIL protein therapy significantly reduces prostate tumor size in lab models. The treatment enhances cancer cell death via Piezo1 activation.

This article explores how switching to an automated continuous manufacturing process can improve product yields and quality, lower capital expenditures, reduce facility footprints and minimize waste, ultimately reducing the price tag of biologics.

A new study reveals that Mitofusin 2 (MFN2) plays a crucial role in protein quality control, preventing harmful protein aggregation linked to Charcot-Marie-Tooth disease (CMT). Researchers found that MFN2 mutations disrupt proteostasis.

UVA Cancer Center researchers have explained the failure of immune checkpoint therapy for ovarian cancer by discovering how gut bacteria interfere with the treatment.

A new study reveals that gut bacteria influence brain protein modifications via glycosylation. Researchers identified over 150,000 glycosylated protein forms, uncovering how gut microbes alter neural functions.

Racial disparities in mortality are increasing. This article explores how the production of DNA-edited ethnically diverse stem cell lines for disease research could improve global health equity.

The HUMANOID Center at UC San Diego is pioneering organoid research aimed at improving the reliability and reproducibility of these models, ultimately increasing drug testing accuracy and revolutionizing biomedical science.

New research has identified a promising strategy against treatment-resistant melanoma: inhibiting the S6K2 gene.