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Drug Targets – Multimedia

Rapid Quantitation of AAV Capsids in Bioprocess Development for Gene Therapy Using Octet®️ BLI
Video

Rapid Quantitation of AAV Capsids in Bioprocess Development for Gene Therapy Using Octet®️ BLI

Accelerate bioprocessing in gene therapy. Adeno-associated virus (AAV) capsid quantitation in as little as 15 minutes using Octet® BLI systems. Compare the Octet® AAVX biosensor workflow to that of ELISA at various stages in bioprocess development.
Determine Kinetics Earlier in the Drug Discovery Process
App Note / Case Study

Determine Kinetics Earlier in the Drug Discovery Process

This app note highlights how reliable kinetics and affinity for high-affinity interactions can be obtained from significantly less data than is commonly used.
Kinetic Analysis
Poster

Kinetic Analysis: Spotting the Weakest Binders

Designing and performing assays that accurately measure small molecule binding kinetics is an important part of the drug discovery process. It allows researchers to predict the efficacy of potential novel therapeutics and make quick decisions about weak binders.
Assess Small Molecule Kinetics and Affinity in Just One Step - image
App Note / Case Study

Assess Small Molecule Kinetics and Affinity in Just One Step

This application note demonstrates how reliable kinetics and affinity can be obtained from single measurement data, increasing sample throughput and saving sample material.
Successful SPR Assays
App Note / Case Study

Determining Real-Time Kinetics and Affinity

This compendium serves as a user-friendly reference for assay design on both bio-layer interferometry (BLI) and surface plasmon resonance (SPR) systems.
Target-Based Drug Discovery content piece image
Infographic

Target-Based Drug Discovery

Target-based drug discovery (TBDD) has been the top drug discovery approach for ~30 years. TBDD approaches were developed to improve drug discovery by reducing the costs of bringing a drug to market, increasing throughput and being more straightforward and efficient than other methods.
Revolutionary Binding Kinetics Analysis content piece image
How To Guide

Revolutionary Binding Kinetics Analysis

Conventional bioassays often require labeled detection reagents to provide a measurable readout. However, modifications to molecular structure and/or function can skew results, and non-specific binding of the labels themselves can lead to an unwanted background signal.
Cell Metabolism: A New Avenue in Drug Discovery content piece image
eBook

Uncover New Drug Targets Through Cell Metabolism

Dysfunctional metabolism is associated with a growing number of different disease states. The ability to examine the genes, proteins and pathways that modulate energy metabolism is therefore a promising new avenue for drug discovery.
Consistency is Key to Further Drug Discovery Research content piece image
App Note / Case Study

Consistency is Key to Further Drug Discovery Research

Energy metabolism plays a central role in a wide variety of cellular and physiological processes. Therefore, a deep understanding of how disruption to energy metabolism impacts cells can help in therapeutic drug discovery and development.
Powering Modern Drug Discovery With DNA Synthesis content piece image
Infographic

Powering Modern Drug Discovery With DNA Synthesis

Download this infographic to learn how to optimize protein-based drug discovery using modern silicon-based DNA synthesis.
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