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Drug Targets – Multimedia

Opinionated Science Episode 34: Genetics of Endometriosis, the Birthing Brain and Cancer Vaccines content piece image
Podcast

Opinionated Science Episode 34: Genetics of Endometriosis, the Birthing Brain and Cancer Vaccines

In this episode, the Technology Networks team reviews world-leading research into the mechanisms behind endometriosis, a condition that affects up to 10% of women of reproductive age, but often takes a decade to diagnose. There's also a peek into mom's brain during birth and a new cancer vaccine that harnesses similar technology used to create the Oxford–AstraZeneva COVID-19 vaccine.
Greater Precision for Transformative Drug Discovery content piece image
App Note / Case Study

Greater Precision for Transformative Drug Discovery

Target identification and characterization are key challenges in drug discovery and begin with identifying the function of a possible therapeutic target and its role in the disease.
Drug–Target Binding: Recent Research Developments content piece image
Listicle

Drug–Target Binding: Recent Research Developments

Being able to accurately predict drug–target interactions (DTIs) and drug–target binding affinity (DTBA) is crucial in early drug development and during drug repurposing endeavors. Here, we look at some recent research developments in this space.
How Stem Cells Are Shaping Drug Discovery content piece image
Listicle

How Stem Cells Are Shaping Drug Discovery

Stem cells are increasingly being used in new and innovative ways to improve the drug discovery process – spanning academia, biotech start-ups and large pharmaceutical companies.
Kinetics in Drug Discovery content piece image
eBook

Kinetics in Drug Discovery

Drugs elicit their desired therapeutic effects by interacting with specific disease-related targets. However, to determine exactly how a drug works inside the body it is important to address key questions. What type of drug is being used? How is it being administered? What are the characteristics of the individual taking the drug?
Automated Immunoprecipitation With Seamless Integration to Protein Analysis content piece image
App Note / Case Study

Automated Immunoprecipitation With Seamless Integration to Protein Analysis

Download this app note to discover an automated immunoprecipitation method that offers seamless integration to protein analysis, ensures high yield and reproducibility as well as delivers low nonspecific binding with significant reductions in total and hands-on time.
App Note / Case Study

Binding Kinetics: High Throughput Assay for Kinase Inhibitors

Download this app note to discover more about binding parameters and high-throughput assays in drug development.
App Note / Case Study

Achieve Successful Immunoprecipitation With Dynabeads

Immunoprecipitation in its basic form is very simple, however protein–protein binding often involves transient and weak interactions. It is therefore paramount to use a method that offers rapid binding kinetics and low nonspecific binding.
Breaking COVID-19’s "Clutch" To Stop Its Spread content piece image
Video

Breaking COVID-19’s "Clutch" To Stop Its Spread

Scripps Research chemist Matthew Disney, Ph.D., and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus’ so-called “frameshifting element” to stop the virus from replicating.
App Note / Case Study

Revealing Cellular Metabolic Phenotype and Function Using the Agilent XF Substrate Oxidation Stress Tests

Download this app note to discover how applying the XF Substrate Oxidation Stress Test can determine which substrates are relevant or required for specific cellular functions or phenotypes.
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