Personalized Medicine – News and Features

Technology Networks asked a selection of start-up companies featured in the ELRIG Drug Discovery 2025 Breakthrough Zone how their technology could help realize the full capabilities of precision medicine.

At this year’s American Society of Human Genetics (ASHG) meeting, Ultima Genomics drew attention for its ambitious goal of making large-scale omics research more accessible and affordable.

At ASHG, Illumina launches 5-base and shows exciting results from constellation, a breakthrough technology offering long-range genomic insights from unfragmented DNA.

An international team mapped over 17,000 genetic variants in the LDLR gene, which helps clear “bad” cholesterol from the blood. The findings could improve diagnosis of familial hypercholesterolemia, a common inherited cause of early heart disease.

Researchers at Ulm University Hospital discovered that mutations in the brain’s MC4R gene, which cause obesity, also lower cholesterol and heart disease risk. The study shows brain signaling can directly regulate fat metabolism.

A new bioengineering platform enables the large-scale production of human kidney organoids that can be perfused within pig kidneys, maintaining viability and function without immune rejection.

A study of ~850,000 adults across six ancestries identified 13 genes linked to obesity, including five novel genes not previously associated. These rare, loss-of-function variants affect brain and fat tissue and also influence diabetes risk.

Explore how oligonucleotides are reshaping therapeutics, diagnostics and CRISPR with rapid, scalable and personalized solutions across biotech.

Deep Visual Proteomics integrates high-resolution imaging, AI and ultra-sensitive mass spectrometry to map proteins at single-cell resolution while preserving spatial context.

An AI system has been designed to aid cancer diagnosis, providing insights into subtyping, biomarker quantification, treatment response assessment and prognostic follow-up.