RNA-Seq – News and Features

Researchers discovered that starlet sea anemones reshape their entire bodies during regeneration to maintain their original proportions. Using spatial transcriptomics, the team identified enzymes active throughout the body that realign tissues.

University of Copenhagen researchers uncovered how juvenile hormone regulates caste differentiation in pharaoh ants. By treating worker larvae with the hormone, researchers induced queen-like traits.

Standardized tissue handling is crucial in cancer research, ensuring the preservation of sample integrity and data quality. This enables comprehensive analysis and enhances understanding of cancer biology, aiding therapeutic discoveries.

Researchers mapped gene expression across the mouse intestine, revealing its stability and adaptability to changes like inflammation. The study identified immune-controlled regions and resilient spatial patterns.

Researchers have used whole-genome CRISPR interference screening to identify the “Achilles Heel” of drug-resistant tuberculosis and identify drugs that target these weaknesses to rapidly kill drug-resistant strains.

A thymus atlas reveals that immune foundations are set as early as 12 weeks post-conception. Researchers uncovered key T cell development processes, offering insights for engineering immune cells to treat cancer and autoimmune diseases.

T-cell dysfunction linked to obesity prevents T cells from detecting tumor cells, increasing cancer risk.

Researchers at the Max Perutz Labs have uncovered how marine worms regenerate lost body segments. The study reveals that differentiated cells dedifferentiate into a stem cell-like state to rebuild a growth zone.

Stanford Medicine's SEQUOIA AI analyzes biopsy images to predict tumor gene activity, reducing the need for costly genomic sequencing. With 80% accuracy for some cancers, it offers visual genetic maps for clinicians.

A study reveals distinct brain circuits that psychedelics activate to reduce anxiety without causing hallucinations in mice. By isolating the anti-anxiety effects from hallucinogenic responses, researchers hope to develop safer, targeted treatments.