Bacterial DNA Jiggling Motion Halted Before Cell DeathVideo
Watch how the jiggling motion of bacterial DNA stops when a natural antimicrobial peptide permeates the E. coli membrane. This novel mechanism helps explain why bacteria develop resistance very slowly and may inform the design of new antimicrobial agents.
Understanding P-gp and BCRP Inhibition Assay Design and OutcomesVideo
Key concepts discussed in this webinar will include: - Description of the in vitro test systems used to evaluate P-gp and - BCRP inhibition at Sekisui XenoTech and the advantages/disadvantages of these assays - Description of the test system qualification process that takes places prior to offering these assays in definitive studies - Comparison of IC50 values obtained from the different test systems - Comparison of IC50 and Ki values determined with the vesicle test system - How IC50 and Ki values are used to evaluate clinical relevance
Scientists have engineered pigs that don't carry a virus which has stalled previous pig to human organ transplantation initiatives.Watch Now
Professor Steve Anderton, Concept Life Sciences explains the challenges associated with immunology and immuno-oncology assays.Watch Now