We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Using Stem Cells Models To Understand Effects Of Gene And Environment On Disease

Video   Oct 19, 2016

 

In IMI StemBANCC we are generating the human induced pluripotent stem cell (hIPSC) resources to improve drug discovery in neurological disorders. We have iPSC lines generated from a range of neurodegenerative disorders, neuropsychiatric conditions and pain disorders. We have also developed robust differentiation protocols to generate relevant cell types. A critical step for such tools to have value in drug discovery is to demonstrate that iPSC that can help explain disease mechanisms and identify cellular disease phenotypes. This includes detecting and understanding the effect of gene and environment despite the inherent variance in iPSC based experiments. We have been conducting experiments to explore these issues using migraine and monogenic Alzheimer’s Disease as exemplars.

 
 
 
 

Recommended Videos

Easily Automate High Content Screening Workflows

Video

This brief video shows step by step how PerkinElmer Signals™ Screening automates HCS workflows. Powered by TIBCO Spotfire®, Signals Screening provides an embedded app store for easy access to common software tools for curve fitting, image analysis, and much more. Handle big data for faster, more efficient drug discovery. Plus easily share and re-use your experiments.

WATCH NOW

What Is the Biggest Single-celled Organism?

Video

The elephant is a creature of epic proportions — and yet, it owes its enormity to more than 1,000 trillion microscopic cells. And on the epically small end of things, there are likely millions of unicellular species, yet there are very few we can see with the naked eye. Why is that?

WATCH NOW

Is Cell-cultured Meat Ready for the Mainstream?

Video

Factory farming’s attempts to keep up with increasing meat consumption are likely unsustainable. Meat grown from animal cells is positioning itself as the solution. Can lab-grown meat live up to its lofty promises?

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE