We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Using Stem Cells Models To Understand Effects Of Gene And Environment On Disease

Video   Oct 19, 2016

 

In IMI StemBANCC we are generating the human induced pluripotent stem cell (hIPSC) resources to improve drug discovery in neurological disorders. We have iPSC lines generated from a range of neurodegenerative disorders, neuropsychiatric conditions and pain disorders. We have also developed robust differentiation protocols to generate relevant cell types. A critical step for such tools to have value in drug discovery is to demonstrate that iPSC that can help explain disease mechanisms and identify cellular disease phenotypes. This includes detecting and understanding the effect of gene and environment despite the inherent variance in iPSC based experiments. We have been conducting experiments to explore these issues using migraine and monogenic Alzheimer’s Disease as exemplars.

 
 
 
 

Recommended Videos

Operetta CLS High-Content Analysis System

Video

The Operetta CLS system is part of PerkinElmer's comprehensive HCS portfolio – from HCS systems and microplates to automation and informatics.

WATCH NOW

In Pursuit of a Universal Antivenom

Video

When it comes to venomous snake bites, time is of the essence.
Find out how researchers are working to find an effective and affordable universal antivenom.

WATCH NOW

ULTImate YChemH: a powerful tool for drug target deconvolution

Video

What if I told you Hybrigenics Services can help you make the right decisions and optimize the success rate of your drug discovery and development programs?
Watch how with our animation video and discover our optimized ULTImate YChemH technology for drug target deconvolution.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE