Latest On Demand Webinars
4D-Lipidomics™: Searching for the Fountain of Youth
This webinar will demonstrate Bruker’s fully integrated lipidomics workflow in MetaboScape and outline how novel 4D-lipidomics tools has been used to gain a better understanding of how a sphingolipid mutation in the C. elegans relates to an increased lifespan – or in other words, the fountain of youth.
Lyophilization: Changing the Game for Molecular Diagnostics
Watch this free webinar to learn more about molecular diagnostic assay lyophilization.
Engineering Mucosal Barriers: From Organoids to Organs-on-Chips
Mucosal barriers are the gateways to all internal organs, serving to transport oxygen, nutrients, and waste and at the same time performing enormous feats of protection against infection and other hazardous insults. The explosion of interest in the human microbiome – especially but not only that in the gut – has driven new interest in building human mucosal barrier models.
Generation and Functional Characterization of hiPSC-Derived Cortical and Sensory Neurons
During this webinar, we will discuss our hiPSC-derived cortical and sensory neurons, co-culture and their electrophysiological characterization using microelectrode arrays (MEA). The focus is on the development of disease models, co-culture, pharmacology and neurotoxicity screening.
Generation and Functional Characterization of hiPSC-Derived Cardiomyocytes
During this webinar, we will discuss our hiPSC-derived cardiomyocytes and a custom service we provide for their electrophysiological characterization using microelectrode arrays (MEA). The focus is on the development of disease models and cardiotoxicity screening.
Multicellular Tissue Models and Methods to Identify Tool Compounds for Interrogation of Novel Targets
Watch this webinar to find out more about models designed for cell-to-cell interactions and fragment-based libraries.
Development of a Sensitive SWATH™ MS Workflow To Advance the Characterization of CAR T-Cell Therapies
CAR T-cell therapies are emerging anti-cancer treatments, whereby the patient’s immune cells are engineered to express chimeric antigen receptors (CARs) on their surface. Wider adoption of this therapeutic modality would benefit from innovative technologies that can improve the characterization of raw material quality attributes (MQA) and final product quality attributes (PQA).
A Microphysiological Model of Metastatic Progression
Metastatic disease is the leading cause of mortality in patients with solid tumors. Despite decades of research, we only partially understand the underlying cellular and molecular mechanisms.
Testing on Humans: How To Predict Hepatotoxicity and Drug Clearance Ahead of Clinical Trials Using Liver-on-a-Chip
Current in vitro approaches for investigational toxicology, drug metabolism (DMPK) and safety are limited and are not fully representative of human response; therefore, drugs showing acceptable preclinical toxicity often fail in human clinical trials, and accurately predicting human drug exposure for new compounds is challenging and costly.
Accelerating Biotherapeutic Charge Variant Analysis With a New iCIEF-MS Platform
In order to bring safe, effective protein therapeutics to market, in particular next generation molecules, biopharma development scientists need to analyze critical quality attributes at the intact protein level.