Optimised genome editing of PSCs enabling efficient production of disease models

Webinar

 
Optimised genome editing of PSCs enabling efficient production of disease models
 

Therapeutic development for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficacious and safe compounds once tested in humans. 

Here we discuss strategies that leverage induced pluripotent stem cells (iPSCs) to increase the relevance of human cell models for these in vitro approaches. We review current advances in genome engineering to pivot from challenges with delivery, identification and selection and subsequent clonal outgrowth by leveraging tools to consistently and reliably generate knock-out and knock-in models for use in target or compound identification. 


Attend this Webinar to:

  • Elucidate effective strategies for building disease models predictive of in vitro and in vivo results leveraging induced pluripotent stem cells (iPSCs)
  • Review current advances in genome engineering to alleviate challenges with delivery, identification and selection and subsequent clonal outgrowth
  • Walk away with a reproducible workflow for successful development of disease models utilizing genome editing and stem cells

 
 
 
 

Comments | 0 ADD COMMENT

Like what you just read? You can find similar content on the communities below.

Biopharma Drug Discovery Genomics Research Neuroscience

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE

We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy