We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Advertisement

Testing on Humans: How To Predict Hepatotoxicity and Drug Clearance Ahead of Clinical Trials Using Liver-on-a-Chip

Webinar

 
Testing on Humans: How To Predict Hepatotoxicity and Drug Clearance Ahead of Clinical Trials Using Liver-on-a-Chip
 

Who's speaking at this Webinar?

Dr Tomasz Kostrzewski
Director Biology, CN-BIO
 

Current in vitro approaches for investigational toxicology, drug metabolism (DMPK) and safety are limited and are not fully representative of human response; therefore, drugs showing acceptable preclinical toxicity often fail in human clinical trials, and accurately predicting human drug exposure for new compounds is challenging and costly.

Microphysiological Systems (MPS), or Organ-on-chip (OOC) technologies are a trending way to bridge the gap between traditional DMPK/toxicology assays and human trials by providing more robust and reliable data that translate into clinical outcomes.

CN Bio offers preclinical investigational toxicology and DMPK services using its proprietary, industry-proven PhysioMimix™ OOC technology and liver-on-a-chip model.

In this webinar, we will share our latest advances in investigational toxicology, drug clearance and drug safety, highlighting how the translatable, human-relevant data generated using CN Bio’s liver-on-a-chip model can be used to support (or call into question) the conclusions of internal pre-clinical studies, helping you to make data driven decisions with greater confidence.

Attend this webinar to learn about: 

  • Developing liver-on-chip MPS systems and comparison to traditional in vitro liver approaches
  • Modeling human hepatotoxicity prediction using liver-MPS
  • Modeling human drug clearance using liver-MPS
  • Data validating and translatability between organ-on-chips and human
  • Accessing CN Bio MPS technology

 
 
 
Advertisement
 

Like what you just read? You can find similar content on the communities below.

Biopharma Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE