Latest Whitepapers

Cell-based chimeric antigen receptor (CAR) T-cell therapies have rapidly advanced from preclinical research. This success has driven an influx of companies to further develop CAR T-cell constructs to make them more effective, safe and persistent.

At high levels, host cell proteins (HCPs) can cause immunogenic responses and reduced efficacy of biologics, so it is imperative to have an effective, robust HCP assay to detect them and mitigate these effects.

While common laboratory plastics are generally regarded as inert by researchers, some commonly used products such as pipette tips and sample tubes have been reported to leach chemical compounds including oleamide, erucamide and DiHEMDA.

With time a precious commodity and ever-increasing regulatory scrutiny, pharmaceutical laboratories are always on the lookout for simple solutions to make their routine tasks easier.

Download this whitepaper to learn more about the three types of incubator monitoring, the level of data and visibility your incubator provides as well as monitoring physiological pH.

Download this whitepaper to discover how a cell sorter can provide precise sorting while maintaining low droplet charge voltages and also handle very high event and sort rates.

Download this whitepaper to discover how third generation sequencing can identify disease-causing variants with complex genetic etiology, detect SARS-CoV-2 and provide novel genetic insights.

Many regulatory guidelines state that cell banks and cultures used in the production of biologics must be tested for mycoplasma. Mycoplasma infections can cause severe problems in manufacturing as these organisms can alter DNA, RNA and modify host cell plasma membrane antigens.

Bioconjugation is the chemical linking of two biomolecules to form a single hybrid that retains the biological activity of each component, yet provides a novel function that is not possible with each individual biomolecule.

Proteins are one of the most vital parts of living organisms with many functions, using the latest proteomics methods it is now possible to understand how protein changes in our body influence health and disease, particularly during ageing.