Isolating Exosomes for Cancer Diagnostics

Article

Exosomes offer a promising avenue for the minimally invasive diagnosis and monitoring of a range of cancers. Overcoming the challenges of isolating these small vesicles from biofluids could lead to wider adoption of exosome technologies in the clinic, and eventually translate into earlier detection and improved treatment plans for cancer patients.

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Liquid Biopsies Coming of Age

Article

Based on the analysis of cells, genes, and chemical signals in body fluids, liquid biopsies provide timely, actionable information on disease states while eliminating the high cost and risks of tissue biopsies. Gene amplification through polymerase chain reaction and related techniques offer these benefits with the added advantage of amplifying low-abundance species. This article looks at the state of the art in PCR-based liquid biopsies, including a discussion of the technique's limitations.

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Smartphones: Making Diagnostics Mobile

Article

Since the introduction of the first iPhone in 2007, smartphones have transformed many aspects of society, changing the way people communicate, shop and access entertainment. The impact they could have on global health is also increasingly being realised.

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Top Female Scientific Discoveries

Quiz

Celebrate International Women's Day with a Quiz about Top Female Scientists

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Possible Biomarker to Identify Who Would Benefit from Immunotherapy
Possible Biomarker to Identify Who Would Benefit from Immunotherapy
News

While immunotherapy has made a big impact on cancer treatment, the fact remains that only about a quarter of patients respond to these treatments. In a new study, researchers examined tissue samples from melanoma and ovarian cancer patients treated with immunotherapies and found a link between the percentage of antigen-presenting cells expressing PD-L1 and an objective clinical response to treatment.

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"Cell Quake Elastography" Maps Elasticity of Cell Components
"Cell Quake Elastography" Maps Elasticity of Cell Components
News

In somewhat the same way that seismologists use the vibrations of planet Earth to characterize its deep structure, scientists have discovered a way to use vibrations within cells to identify their mechanical properties.

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Tweak to Technique Could Bolster Disease Detection
Tweak to Technique Could Bolster Disease Detection
News

A team of Stanford researchers has developed a technique that they hope could more precisely detect diseases or disorders such as cancer or a heart attack.

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Diagnosing Immunity to Ebola With Paper Tests & Smartphones
Diagnosing Immunity to Ebola With Paper Tests & Smartphones
News

A promising new approach to detect immunity to Ebola virus infection has been developed by researchers from i-sense in a collaboration between UCL and Imperial College London.

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Immune Cells That Keep Gut Fungi Under Control Identified
Immune Cells That Keep Gut Fungi Under Control Identified
News

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

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Antibiotic Micro-beads Fight Infection in Joint Replacements
Antibiotic Micro-beads Fight Infection in Joint Replacements
News

More than 1 million people undergo total joint replacements each year, and nearly 10,000 will develop infections. To reduce this infection risk, an orthopedic surgeon has created small antibiotic beads that are implanted with the new joint to slowly release medicine for several weeks.

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