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Top 10 Diagnostics News Stories of 2019

List

2019 has seen some exciting developments in diagnostics. In this list, we look at ten of the most-read stories in the field published on Technology Networks over the last year.

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Advances in PCR Diagnostics for Cancer and Medical Mycology

Article

From detecting cancer to microbial infections, and now even fungal infections, PCR has become the gold standard of analyzing gene expression. In this article, we explore how PCR is used as a novel diagnostic strategy to identify clinically important yeast species, as well as to detect mutations that could guide therapeutic decisions for lung cancer patients.

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The Longitude Challenge - Developing a Diagnostic Test To Fight Antimicrobial Resistance

Blog

We recently spoke with Daniel Berman, Global Health Lead at Nesta Challenges, to learn about the Longitude Prize, a £10 million prize fund with an £8 million pay-out, which will be awarded to a team that invents an affordable, accurate, fast and easy-to-use test for bacterial infections.

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How We're Using Dogs To Sniff Out Malaria

Video

What if we could diagnose some of the world's deadliest diseases by the smells our bodies give off? In a fascinating talk and live demo, biologist James Logan introduces Freya, a malaria-sniffing dog, to show how we can harness the awesome powers of animal scent to detect chemical signatures associated with infection – and change the way we diagnose disease.

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The Value and Versatility of Clinical Flow Cytometry

Article

Flow cytometry has inarguable potential as a clinical tool for disease diagnosis, prognosis, and therapeutic monitoring. However, some challenges remain in translating the full promise of FCM into clinical practice. Here, some of the current clinical applications of FCM will be discussed, as well as some of the compelling new applications being researched.

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Blood Test Could Predict Onset of Tuberculosis

News

Scientists at UCL have shown a blood test could predict the onset of tuberculosis three to six months before people become unwell, a finding which could help better target antibiotics and save countless lives.

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Imaging Approach Refines Breast Cancer Classification
News

An imaging approach developed at UZH enables the study of breast cancer tissue in greater detail. It uses 35 biomarkers to identify the different cell types in breast tumors and its surrounding area compared to the current standard of testing single markers. This increases the precision of tumor analysis and classification - and improves personalized diagnostics for breast cancer patients.

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New Glaucoma Test To Help Prevent Blindness
News

After identifying 107 genes that increase a person’s risk of developing the eye disease glaucoma, researchers have now developed a genetic test to detect those at risk of going blind from it.

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Magnetized Molecules Help Monitor Breast Cancer
News

A new type of scan has been developed that involves magnetizing molecules – it allows physicians to observe in real-time which regions of a breast tumor are active.

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Global Alarm Over Spread of Novel Coronavirus
Article

Today an emergency committee convened in Geneva to discuss whether or not the current outbreak of a novel coronavirus in China should be declared a “public health emergency of international concern.”

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Missense, Nonsense and Frameshift Mutations: A Genetic Guide
Article

If you want to build a foundational understanding of genomics in both health and disease, it's important to be able to distinguish between the different type of genetic mutations that can occur. Here, we take a look at some of the mutations that can be encountered and the impact they have on the genome.

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Incidence vs Prevalence
Article

In epidemiology, prevalence and incidence are among the most fundamental measures when it comes to monitoring disease. But do you know what they mean or how and why they are important? This article takes a look at disease prevalence and incidence, what this information tells us and how it can be used.

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Liquid Biopsy: Guide, Applications and Techniques
Article

Liquid biopsies are tests conducted on blood samples that examine biomarkers shed by tumors, such as cancer cells or pieces of tumor DNA. The data from liquid biopsies can be used in place of or alongside that of traditional surgical biopsies. In this article, we review the theory behind liquid biopsies and their applications in cancer medicine.

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2DLC in Food Safety and Traceability
Article

With so many potential routes for food contaminants, both natural and otherwise, having the tools to detect them, determine the source of the problem and prevent them from reaching the consumer is therefore vitally important. In this article, we explore how 2DLC is being implemented to improve food safety and contaminant traceability.

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Should Infectious Diseases Be Made Notifiable? The Good, the Bad and the Ugly
Article

At first glance this question might seem like a no-brainer. Surely if you make an infectious disease notifiable then you are better able to contain infection and prevent it spreading, right? Unfortunately, whilst the principle seems simple, the reality is far less so. Here we take a look at the different facets and implications of making an infectious disease notifiable.

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