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Latest Application Notes

Application Note

Investigation of Cell Migration using a High Density Cell Exclusion Assay and Automated Microplate Imager

This application note investigates the use of high density cell exclusion assays for examination of cell migration.
Application Note

Chromatrap® – Targeting the Epigenetic Landscape Alongside Low Abundant Transcription Factor Recruitment

This application note demonstrates the sensitivity, selectivity and reproducibility of solid phase Chromatrap®, as an assay for Chromatin IP from low cell numbers.
Application Note

Real-time Monitoring of Genetically Encoded Redox Probes in Mammalian Cell Monolayers

In this application note we show that the PHERAstar FS reader enables roGFP2-based measurements in mammalian cell monolayers grown in 96-well imaging plates.
Application Note

Blood Cell Analysis with the Moxi Z

This application note discusses how Moxi Z can generate important metrics from blood samples for non-clinical analysis including red blood cell (RBC) counts, mean corpuscular volume (MCV), white blood cell (WBC) total counts and peripheral blood mononuclear cell (PBMC) size distributions and counts.
Application Note

Whole-Mount Slide Imaging in Traumatic Brain Injury Research

This application note describes how the TissueScope™ solution provides researchers with the opportunity to effectively map the entire brain, and link detailed cytoarchitectural maps with functional imaging data.
Application Note

Ensuring Sectioning Quality in TMA Analysis for the Human Protein Atlas Project

This article describes how the tissue microarrays and slides are made, and how a rotary microtome with different cutting modes and an automated Section Transfer System together ensure that high-quality, reproducible sections are generated.
Application Note

Sectioning of Bone as a Specialist Histology Specimen

This application note discusses how the Thermo Scientific HM355S and Finesse ME+ Automated Microtomes deliver quality sections from bone tissue.
Application Note

Proteomic Analysis of Laser Microdissected FFPE Tissue Using Mass Spectrometry

This application note discusses a study which was undertaken to identify candidate protein biomarkers for early detection of endometrial cancer using formalin fixed paraffin embedded tissue samples.
Application Note

Mass Spec Protein Assays in FFPE Tissue

This application note discusses how the Liquid Tissue®-SRM platform makes possible quantitation of proteins and their phosphorylation states by mass spectrometry using small amounts of laser microdissected FFPE tissue.
Application Note

Triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS

This document provides detailed information about triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS systems.
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