Latest Application Notes
Investigation of Cell Migration using a High Density Cell Exclusion Assay and Automated Microplate Imager
This application note investigates the use of high density cell exclusion assays for examination of cell migration.
Chromatrap® – Targeting the Epigenetic Landscape Alongside Low Abundant Transcription Factor Recruitment
This application note demonstrates the sensitivity, selectivity and reproducibility of solid phase Chromatrap®, as an assay for Chromatin IP from low cell numbers.
Real-time Monitoring of Genetically Encoded Redox Probes in Mammalian Cell Monolayers
In this application note we show that the PHERAstar FS reader enables roGFP2-based measurements in mammalian cell monolayers grown in 96-well imaging plates.
Blood Cell Analysis with the Moxi Z
This application note discusses how Moxi Z can generate important metrics from blood samples for non-clinical analysis including red blood cell (RBC) counts, mean corpuscular volume (MCV), white blood cell (WBC) total counts and peripheral blood mononuclear cell (PBMC) size distributions and counts.
Whole-Mount Slide Imaging in Traumatic Brain Injury Research
This application note describes how the TissueScope™ solution provides researchers with the opportunity to effectively map the entire brain, and link detailed cytoarchitectural maps with functional imaging data.
Ensuring Sectioning Quality in TMA Analysis for the Human Protein Atlas Project
This article describes how the tissue microarrays and slides are made, and how a rotary microtome with different cutting modes and an automated Section Transfer System together ensure that high-quality, reproducible sections are generated.
Sectioning of Bone as a Specialist Histology Specimen
This application note discusses how the Thermo Scientific HM355S and Finesse ME+ Automated Microtomes deliver quality sections from bone tissue.
Proteomic Analysis of Laser Microdissected FFPE Tissue Using Mass Spectrometry
This application note discusses a study which was undertaken to identify candidate protein biomarkers for early detection of endometrial cancer using formalin fixed paraffin embedded tissue samples.
Mass Spec Protein Assays in FFPE Tissue
This application note discusses how the Liquid Tissue®-SRM platform makes possible quantitation of proteins and their phosphorylation states by mass spectrometry using small amounts of laser microdissected FFPE tissue.
Triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS
This document provides detailed information about triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS systems.