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Latest App Notes & Case Studies

App Note / Case Study

Evaluation of the IntelliQube® for Gene Expression Analysis using a One-Step RT-PCR Workflow

A recent study demonstrates the ability of the IntelliQube® and associated Array Tape®, to process RNA samples using a one-step RT-PCR workflow, opening the door to a variety of RNA screening applications including gene expression or viral detection and quantification.
App Note / Case Study

Rapid Point of use DNAble® Assay for Salmonella enterica using the Douglas Scientific® AmpliFire®

With greater portability than real-time PCR instrumentation, the AmpliFire produces rapid and accurate results in the field or in the lab without cumbersome equipment or reagents. In a recent study, the AmpliFire® accurately detected the presence of Salmonella enterica using both purified genomic DNA and a crude sample preparation method, making it a powerful tool for point of use applications.
App Note / Case Study

Microbial Detection and Quantification Using the IntelliQube® from Douglas Scientific®

Nucleic Acid Testing (NAT) is a powerful tool for the quantification of microorganisms and are used in many fields. In this study commercially available microbial NAT kits were successfully miniaturized from 20 µL to 1.6 µL reaction volumes using the IntelliQube. The IntelliQube delivers efficient and economical high throughput sample processing for microbial qPCR applications.
App Note / Case Study

Evaluation of a New Accurate, Automated and Cost-effective Approach for the Analysis of Pharmacologically Important Copy Number Variation

The IntelliQube® from Douglas Scientific® is designed to address the need for accurate and reliable results for studies such as CNV determination.
App Note / Case Study

Investigation of Cell Migration using a High Density Cell Exclusion Assay and Automated Microplate Imager

This application note investigates the use of high density cell exclusion assays for examination of cell migration.
App Note / Case Study

Chromatrap® – Targeting the Epigenetic Landscape Alongside Low Abundant Transcription Factor Recruitment

This application note demonstrates the sensitivity, selectivity and reproducibility of solid phase Chromatrap®, as an assay for Chromatin IP from low cell numbers.
App Note / Case Study

Real-time Monitoring of Genetically Encoded Redox Probes in Mammalian Cell Monolayers

In this application note we show that the PHERAstar FS reader enables roGFP2-based measurements in mammalian cell monolayers grown in 96-well imaging plates.
App Note / Case Study

Blood Cell Analysis with the Moxi Z

This application note discusses how Moxi Z can generate important metrics from blood samples for non-clinical analysis including red blood cell (RBC) counts, mean corpuscular volume (MCV), white blood cell (WBC) total counts and peripheral blood mononuclear cell (PBMC) size distributions and counts.
App Note / Case Study

Whole-Mount Slide Imaging in Traumatic Brain Injury Research

This application note describes how the TissueScope™ solution provides researchers with the opportunity to effectively map the entire brain, and link detailed cytoarchitectural maps with functional imaging data.
App Note / Case Study

Ensuring Sectioning Quality in TMA Analysis for the Human Protein Atlas Project

This article describes how the tissue microarrays and slides are made, and how a rotary microtome with different cutting modes and an automated Section Transfer System together ensure that high-quality, reproducible sections are generated.
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