Latest App Notes & Case Studies

This application note describes how the TissueScope™ solution provides researchers with the opportunity to effectively map the entire brain, and link detailed cytoarchitectural maps with functional imaging data.

This article describes how the tissue microarrays and slides are made, and how a rotary microtome with different cutting modes and an automated Section Transfer System together ensure that high-quality, reproducible sections are generated.

This application note discusses how the Thermo Scientific HM355S and Finesse ME+ Automated Microtomes deliver quality sections from bone tissue.

This application note discusses a study which was undertaken to identify candidate protein biomarkers for early detection of endometrial cancer using formalin fixed paraffin embedded tissue samples.

This application note discusses how the Liquid Tissue®-SRM platform makes possible quantitation of proteins and their phosphorylation states by mass spectrometry using small amounts of laser microdissected FFPE tissue.

This document provides detailed information about triggering with the Leica TCS SP5, TCS SP5 II and DM6000 CFS systems.

This application note shows the methodology for viewing and evaluating captured cells on screen.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.

For accurate, reproducible quantification of testosterone, a growing number of laboratories are shifting from immunoassay to liquid chromatography coupled with tandem mass spectrometry. This application note describes the preparation of serum samples for subsequent LC-MS analysis of testosterone, focusing on a streamlined workflow suitable for automation.

Housekeeping proteins (HKP) are typically used as loading controls because it is assumed that the HKP expression level remains consistent across samples. However, there is evidence that HKP expression levels change in many scenarios, including siRNA treatment, cell death, cell differentiation, etc.