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Achieve a More Sensitive Quantification of Wide Linear Dynamic Range Tripeptides

Achieve a More Sensitive Quantification of Wide Linear Dynamic Range Tripeptides
Credit : Istock

Drug discovery is increasingly focusing on low-dose therapeutics, creating demand for highly sensitive analytical methods. Despite the capabilities of modern TOF platforms, current systems lack wide linear dynamic range and sensitivity is limited by the loss of ion transmission between pulses.

Using the latest ZenoTOF systems enhanced workflows can achieve lower limits of quantification. This approach reduces ion loss during the pulse cycle, increases MS/MS sampling efficiency and improves signal-to-noise ratio.

This application note introduces a reliable workflow for tripeptide analysis that can ensure high sensitivity and enhanced selectivity.

Download this application note to discover:

  • The latest quantification methods for tripeptides 
  • A practical approach that offers wide linear dynamic range
  • Streamlined MS workflows for data acquisition and processing

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