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Scientists Explore the Molecular Mechanics that Drive us to Sleep
Article

Scientists describe how phosphorylation of 80 synaptic proteins drives our sleep/wake cycles

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Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells
Article

Although cisplatin is clinically proven to combat numerous human cancers – bladder, head and neck, lung, ovarian, testicular – resistance to treatment remains a key challenge, and cisplatin patients can often relapse. Having the ability to determine the cellular uptake of cisplatin is key to developing novel strategies to increase tumor cell sensitivity to cisplatin.

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Cryo-EM and CX-MS: The Power Couple of Proteomics
Article

An ambitious new workflow has married two cutting-edge proteomic analysis techniques to improve imaging of large protein assemblies. The combination of electron cryo-microscopy (cryo-EM) and cross-linking coupled mass spectrometry (CX-MS) allows deeper interrogation of protein structures to a level of detail that the techniques are incapable of obtaining on their own.

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Henrietta Lacks: The Mother of Modern Medicine
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A portrait of Henrietta Lacks has recently been unveiled at the Smithsonian’s National Portrait Gallery, to recognize her life and the vital contributions HeLa cells have made to science.

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How Mass Spectrometry Has Changed the Cancer Diagnostics Game
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Although histopathology is still the gold standard for diagnosing cancer, molecular analysis using MS has gained traction in recent years for detecting tumors, monitoring progression, and even predicting treatment response.

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A Hangover Pill? Tests on drunk mice show promise
Article

Scientists create capsules filled with natural enzymes usually found in liver cells to help the body process the alcohol faster.

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Catching Cancer Early: How Improving Cancer Awareness Can Prevent Delayed Diagnosis
Article

When it comes to cancer detection and diagnosis – the earlier the better. Cancer that remains undiagnosed until it is within ‘advanced’ stages is harder to treat successfully.

15-40 Connection’s mission is to empower patients and promote cancer conversation to ultimately improve cancer survival rates.

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Tech Solutions for Drinking Water Analysis
Article

Improved access to clean and safe drinking water is key for health and survival and has been classified as a human right. Here, we take a look at some of the novel solutions, both hi-tech and low-tech, that scientists are designing to help monitor drinking water source safety.

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New Tools for Combating Antibiotic Resistance
Article

Antibiotic resistance is a serious health problem, causing illnesses that were once easily treatable with antibiotics to morph into dangerous infections, leading to serious disability or even death. To help fight this growing threat, diagnostics companies are developing new tools and techniques that are playing a crucial role in quickly identifying infectious organisms and preventing the inappropriate use of antibiotics.

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The Future for PCR Diagnostics
Article

The Nobel Prize winning polymerase chain reaction (PCR) technique revolutionized molecular biology on its invention in 1986 and it has done the same for medical diagnostics over the last 15 years. Being able to copy and multiply specific target DNA molecules has opened the door to diagnosing diseases across multiple areas quickly, accurately, and as time progresses at lower cost.

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