We are entering uncharted territory in biopharmaceutical development. Emerging new classes of treatments are harnessing the natural power of viruses and cells and engineering them to fight human diseases. As our arsenal of conventional therapies begins to fail, a new army of biotherapeutics is on the horizon. Here, we look at two new classes of treatments leading the charge.READ MORE
A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.READ MORE
In this article, we explore two novel high-throughput analytical methods based on liquid chromatography-mass spectrometry (LC-MS) analysis that can augment early drug screening and biomarker detection in the clinic.READ MORE
To achieve regulatory compliance and authorization for sale in Europe, every medical device must be supported by a Clinical Evaluation Report which documents the entire clinical evaluation process. Read on for recommendations on how manufacturers can keep up with the changing regulation landscape.READ MORE
As part of the host-pathogen arms race, viruses are continually evolving to evade the host immune response, be it from previous infection or immunity acquired through vaccination. Here we take a look at the processes of antigenic drift and antigenic shift.READ MORE
To pick apart the differences between individual cells in complex multicellular organisms, we need to look at cells one-by-one. This article takes a look at how several scientists in North America are using single cell proteomics (SCP) technologies to discern disease pathogenesis and enhance directed stem-cell differentiation.READ MORE
When you go to the shops to buy the weekly groceries, it’s quite likely you’ll find yourself thinking about where your food has come from. Is this organic? Is that free-range? You are perhaps less likely to find yourself wondering, “Is this food fake?”READ MORE
The world of microfluidics has generated a host of intricate tools on a microscale, ranging from cheap paper-based lateral flow tests to organ-on-a-chip models designed to facilitate personalized diagnostic tests.
This article explores the extent to which microfluidic tools are filling a gap in clinical and point-of-care diagnostics, and touches on how microfluidics could improve the drug discovery process.
Integrating new technologies into laboratory workflows can be a complex transition. This article outlines why, when it comes to diagnosing infections, it's an investment worth making.READ MORE
Mass spectrometry imaging (MSI) is a powerful tool increasingly being used in many fields including cancer research, biomarker discovery and drug development. This article explains why MSI is the technique of choice in many labs, discusses its use in research, and covers how some inherent challenges are being addressed.READ MORE