The fight against antibiotic resistance is real and is something we all have a responsibility in tackling. In fact, Antibiotic resistance kills an estimated 700,000 people each year and has fuelled the re-emergence of illnesses that had become a rarity in many parts of the world.READ MORE
In this article, we provide practical guidance for the application of differential scanning calorimetry (DSC), a core technique for studying the stability and higher order structure (HOS) of proteins. We explain how DSC works, and highlight good practice for ensuring optimal data quality. The interpretation and value of the resulting data is also discussed.READ MORE
The imaging of biological samples, or bioimaging, plays a key role in current life science research, enabling scientists to analyze molecules, cells and tissues from a range of living systems.READ MORE
Mass spectrometry has evolved as a prevailing technique for both the characterization of biotherapeutics and identification of protein variants and post-translational modifications.READ MORE
Since its origins in the 1960s, the biosensors field has grown to encompass a wide range of sensors, from enzyme-based to immunosensors to DNA biosensors. Along with this, a diverse set of applications have flourished, with biosensors finding roles in food safety, medical diagnostics, and environmental analysis to name just a few.
Aflatoxins have been an issue in food and feed since the 1970’s, but the first global effort to regulate them took place in 2003. Aflatoxin B1 is by far the most prevalent and potent sub-type. Accordingly, maximum levels for B1 are set lower than total aflatoxin levels which highlights the need to test these two measures independently.READ MORE
Medicine has been moving away from a "one-size-fits-all" approach towards predictive, preventive and treatment strategies tailored to the individual - precision medicine. Quantitative proteomics is playing an important part in this process but there are still some areas in which improvements must be seen before assays are likely to be routinely available to clinicians and patients.READ MORE
Exosomes offer a promising avenue for the minimally invasive diagnosis and monitoring of a range of cancers. Overcoming the challenges of isolating these small vesicles from biofluids could lead to wider adoption of exosome technologies in the clinic, and eventually translate into earlier detection and improved treatment plans for cancer patients.READ MORE