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Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells
Although cisplatin is clinically proven to combat numerous human cancers – bladder, head and neck, lung, ovarian, testicular – resistance to treatment remains a key challenge, and cisplatin patients can often relapse. Having the ability to determine the cellular uptake of cisplatin is key to developing novel strategies to increase tumor cell sensitivity to cisplatin.
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Cryo-EM and CX-MS: The Power Couple of Proteomics
An ambitious new workflow has married two cutting-edge proteomic analysis techniques to improve imaging of large protein assemblies. The combination of electron cryo-microscopy (cryo-EM) and cross-linking coupled mass spectrometry (CX-MS) allows deeper interrogation of protein structures to a level of detail that the techniques are incapable of obtaining on their own.
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Understanding the Mechanisms of Streptococcal Infection and Disease
Professor Shiranee Sriskandan is a Clinical Professor of Infectious Diseases at Imperial College London. She leads a team focused on the mechanisms by which streptococcal infections cause serious disease. As well as her research work, Professor Sriskandan undertakes teaching within the University and is also a medic at Hammersmith Hospital.
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Liquid Biopsy as an Alternative to Traditional Tissue Biopsy
Since co-founding Vortex Biosciences in 2012, Elodie Sollier-Christen, PhD has continued to be recognized for her work within the field of microfluidics, her expertise focused on the development of microfluidic devices for biological applications. Her determination to make a difference to the field of cancer diagnostics has driven her to successfully transform a microfluidic research platform in to a commercial product for liquid biopsy.
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Henrietta Lacks: The Mother of Modern Medicine
A portrait of Henrietta Lacks has recently been unveiled at the Smithsonian’s National Portrait Gallery, to recognize her life and the vital contributions HeLa cells have made to science.
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How Mass Spectrometry Has Changed the Cancer Diagnostics Game
Although histopathology is still the gold standard for diagnosing cancer, molecular analysis using MS has gained traction in recent years for detecting tumors, monitoring progression, and even predicting treatment response.
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A Hangover Pill? Tests on drunk mice show promise
Scientists create capsules filled with natural enzymes usually found in liver cells to help the body process the alcohol faster.
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Catching Cancer Early: How Improving Cancer Awareness Can Prevent Delayed Diagnosis
When it comes to cancer detection and diagnosis – the earlier the better. Cancer that remains undiagnosed until it is within ‘advanced’ stages is harder to treat successfully.
15-40 Connection’s mission is to empower patients and promote cancer conversation to ultimately improve cancer survival rates.
15-40 Connection’s mission is to empower patients and promote cancer conversation to ultimately improve cancer survival rates.
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Tech Solutions for Drinking Water Analysis
Improved access to clean and safe drinking water is key for health and survival and has been classified as a human right. Here, we take a look at some of the novel solutions, both hi-tech and low-tech, that scientists are designing to help monitor drinking water source safety.
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New Tools for Combating Antibiotic Resistance
Antibiotic resistance is a serious health problem, causing illnesses that were once easily treatable with antibiotics to morph into dangerous infections, leading to serious disability or even death. To help fight this growing threat, diagnostics companies are developing new tools and techniques that are playing a crucial role in quickly identifying infectious organisms and preventing the inappropriate use of antibiotics.
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