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ddPCR Brings Confidence to Leukemia Monitoring

Article   Jan 03, 2019 | by Chinmay Sheth, Marketing Manager, Clinical Diagnostics at Bio-Rad Laboratories

 
Quantifying Minimal Residual Disease in Chronic Myeloid Leukemia

Droplet digital PCR is sensitive enough to detect rare DNA sequences such as BCR-ABL gene fusions. From left: the sample is partitioned into 20,000 nanoliter-sized droplets; each droplet undergoes PCR amplification to endpoint, and droplets that contain the target DNA fluoresce; positive droplets are counted to enable absolute and precise quantification of the target sequence.

 
 
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