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ddPCR Brings Confidence to Leukemia Monitoring

Article   Jan 03, 2019 | by Chinmay Sheth, Marketing Manager, Clinical Diagnostics at Bio-Rad Laboratories

Quantifying Minimal Residual Disease in Chronic Myeloid Leukemia

Droplet digital PCR is sensitive enough to detect rare DNA sequences such as BCR-ABL gene fusions. From left: the sample is partitioned into 20,000 nanoliter-sized droplets; each droplet undergoes PCR amplification to endpoint, and droplets that contain the target DNA fluoresce; positive droplets are counted to enable absolute and precise quantification of the target sequence.



Francis Mojica: The Modest Microbiologist Who Discovered and Named CRISPR


Kicking off Technology Networks Explores the CRISPR Revolution, Professor Mojica, or "Francis", takes us on a journey back to the original research that, despite being deemed "crazy" by members of the scientific community at the time, led to the CRISPR revolution that is anticipated to edit evolution forever.


Feeling Like a Fraud: Impostor Syndrome in STEM


Impostor syndrome is experienced by millions of people around the world cross culturally, and describes difficulty internalizing one's accomplishments or abilities, and instead attributing their success to other factors. In this article, we explore the prevalence of impostor syndrome in STEM and the impact it has on the scientific community.


Exploring the Latest in CRISPR and Stem Cell Research


Thus far, the feasibility to edit stem cells using CRISPR technology has been demonstrated in two key areas: modeling and investigating human cell states and human diseases, and regenerative medicine. In this article, we explore some of the latest research in these spaces and the approaches that scientists are adopting to overcome challenges in the field.



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