Blog

HPV-Positive Oropharyngeal Cancers: Predicting Treatment Response Using ddPCR

HPV-Positive Oropharyngeal Cancers: Predicting Treatment Response Using ddPCR

Blog

During this year’s AACR Annual Meeting we spoke to Julianna Supplee, Research Technician at the Robert and Renée Belfer Center for Applied Cancer Science at Dana-Farber Cancer Institute, to learn more about the team’s most recent study on the use of plasma HPV cell-free DNA as an early predictor of treatment response in patients with advanced oropharyngeal cancer.

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Using Cell-free DNA as a Marker for Liver Cancer Diagnosis

Using Cell-free DNA as a Marker for Liver Cancer Diagnosis

Blog

During this year’s AACR conference we spoke to Kang Zhang, M.D., Ph.D. from the University of California, San Diego about the collaborative work he has been doing with the Laboratory for Advanced Medicine. He discusses their recent study findings on the use of a blood-based method to look at cell-free DNA as a marker for liver cancer diagnosis and prognosis.

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Accelerating Proteome Analysis With PASEF: A Unique and Sensitive Technique

Accelerating Proteome Analysis With PASEF: A Unique and Sensitive Technique

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Understanding the proteome is a fundamental challenge of biology. Here, Bruker Daltonics' Gary Kruppa and Scarlet Koch outline a new method, Parallel Accumulation Serial Fragmentation (PASEF) that offers faster, more sensitive and more robust proteome analysis, giving scientists the potential to discover low-level, biologically significant proteins and validate them in research.

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Accelerating the Development of Organs-on-Chips

Accelerating the Development of Organs-on-Chips

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Emulate, Inc. and AstraZeneca recently announced they have formed a collaborative partnership which will see Emulate's Organs-on-Chips technology embedded in AstraZeneca's Innovative Medicines and Early Development Biotech Unit.

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AI and Humans: Working Together to Improve Diagnosis

AI and Humans: Working Together to Improve Diagnosis

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To learn more about the impact AI has already had on diagnostics and health services, as well as some of its future capabilities, we spoke to Chris Scarisbrick.

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How Native MS and Charge Algorithms Can Improve Protein Analysis

How Native MS and Charge Algorithms Can Improve Protein Analysis

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Native Mass Spectrometry (MS) can be used to examine proteins in their natural, folded forms. In this blog, Marshall Bern, Ph.D., the Vice President of Research and Co-Founder of Protein Metrics, discusses how advances in this technique are being paired with cutting-edge charge deconvolution algorithms to improve analysis of antibodies and plasma glycoproteins.

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A New Generation of Flow Cytometers Advances Multiomics

A New Generation of Flow Cytometers Advances Multiomics

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Flow cytometry allows the analysis of physical and biochemical features of cells. Advances in machine that can characterize and sort cells will allow researchers to look deeper than ever before into the proteome and transcriptome. We talk with Bob Balderas, VP Market Development at BD on how the cutting-edge machines like the FACSymphony S6 cell sorter incorporate new technology and advance multiomics research.

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Overcoming Challenges in Clinical Microbiology Labs with Informatics and Automation

Overcoming Challenges in Clinical Microbiology Labs with Informatics and Automation

Blog

We spoke to Steve Conly, Vice President & General Manager, Microbiology for BD Diagnostics Systems, to learn more about the challenges facing clinical microbiology labs, and how informatics and automation solutions can help overcome these.

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Newly Discovered Biomarker Could Help Diagnose Hearing Loss Earlier

Newly Discovered Biomarker Could Help Diagnose Hearing Loss Earlier

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In collaboration with UConn, Sensorion have identified the first potential biomarker for noise-induced hearing loss, findings which were recently presented at the 53rd American Neurotology Society Annual Spring Meeting.

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Cinderella and Mass Spectrometry: Insightful Multi-Dimensional Data Analysis

Cinderella and Mass Spectrometry: Insightful Multi-Dimensional Data Analysis

Blog

Proteomics is a powerful technology for analyzing low-abundance proteins for disease research. But it’s stalled by imprecise and often irreproducible data analysis. Here, David Chiang, Founder of Sage-N Research, explains how his company uses multidimensional separation to improve peptide identification in MS/MS.

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