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Industry Insights

DNA Methylation Analysis for Early Detection of Various Cancers
Industry Insight

We recently spoke to Richard Brand, CFO and Dhruvajyoti Roy, Director of Technology from the Laboratory for Advanced Medicine (LAM) to learn more about how LAM is developing methylation-based tests for the early detection and intervention of cancer.

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Why Should Antibodies Be Manufactured Recombinantly?
Industry Insight

Given that bad antibodies are likely to blame for a significant proportion of the reproducibility crisis in science, any efforts to reduce batch-to-batch variability are more than welcome. One company with a plan to help in this area is “Absolute Antibody”, who believe that recombinant antibodies are the way forward. To learn more about making antibodies with recombinant technology, we spoke to Ian Wilkinson, PhD, Chief Scientific Officer.

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Entering the Antibody Lottery: Tips for Avoiding Dubious Sources
Industry Insight

Having reliable antibodies can make or break your assay. However, sourcing the right antibody for the job can sometimes feel like you’re entering the lottery: there are so many on the market, and often they just don’t live up to what was promised. To learn more about antibody validation and its importance, we got in touch with Anthony Couvillon, PhD, Scientific Marketing Project Manager at Cell Signaling Technology.

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Flow Cytometry in the Clinic
Industry Insight

Flow cytometry is a technique used to count and analyze the size, shape and properties of individual cells. Not just a valuable research tool, flow cytometry is also finding its stride in several clinical areas. Following BD Biosciences’ launch of a new sample preparation instrument, we spoke to Stephen Gunstream, VP and general manager, to get his insights on the role of flow cytometry in the clinic.

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Improving Lung Cancer Survival and Alleviating Chemotherapy-induced Neutropenia
Industry Insight

We recently spoke with Dr Lan Huang, CEO at BeyondSpring, a clinical-stage biopharmaceutical company to learn more about the company’s efforts to develop innovative immuno-oncology cancer therapies.

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Scouting Out Microparticles in the Battle With Microplastics
Industry Insight

There are many reasons that one might want to detect microparticles in a sample, and equally many sources from which microparticles may be generated. Of growing interest recently is the identification of microplastics, not just in the environment but also in the food chain. We spoke to Harald Fischer, Marketing Director at WITec, about ParticleScout, their latest Raman-based solution for rapid identification of microparticles, and the role it can play in assisting microplastic studies.

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Releasing the Handbrake on Exosome Applications
Industry Insight

Despite the great excitement about exosomes and their huge diagnostic and therapeutic potential, the technology needed to advance this work is lacking. We spoke to Jim West, CEO of Clara Biotech, who tells us how his team is working to fill that gap.

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Proteogenomics, Precision Medicine and Oncology
Industry Insight

Major advances have occurred in the fields of proteomics and genomics over recent years. Now, scientists are utilizing the technologies from each approach collectively in a novel research area named proteogenomics. We spoke with Alexzander Asea, Professor and Director at Precision Therapeutics Proteogenomics Diagnostics Center, University of Toledo, to learn more about the applications of proteogenomics in precision medicine.

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Calculating Gestational Age With Metabolomics
Industry Insight

Researchers have developed a mathematical model that may offer an alternative to relying on ultrasound information for calculating gestational age. The model, utilizing a "metabolomic fingerprint" approach, may overcome barriers in preterm death research.

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“Mastermind” Scientists Help Diagnose Rare Diseases
Industry Insight

The Rare Genomics Institute announced on Rare Disease Day 2019 that they had used the Mastermind Genomic Search Engine, a clinical decision support tool by Genomenon, to diagnose a rare disease patient. We spoke to Mark Kiel, MD, PhD, Founder and Chief Science Officer at Genomenon and Romina Ortiz, COO at the Rare Genomics Institute, to learn more about the application of this technology in rare diseases.

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