Training

This course aims to provide an introduction to immunology bioinformatics, offer opportunities to explore key methods, tools and resources that can be applied to research. The course will provide participants with an overview of best-practice methods in applying bioinformatics approaches and enable them to become confident users of their own and public domain data. The resources introduced during the course will cover a variety of data types, from genomic and proteomic data; to computational models, biological pathways and reaction information. Participants will gain experience of the analysis pipelines for NGS experiments relevant to immunology, and will be led through an exploration of this data to identify information of interest. Additionally participants will be introduced to how data from a number of sources can be integrated to provide a wider view of their research.

The course will explore a number of bioinformatics resources relevant to immunology including:

• abYsis – antibody discovery system
• 3i Consortium and immunology databases
• IntAct database
• Reactome database
• BioModels database

After this course participants should be able to:

• Locate and search publically available bioinformatics data of interest

• Utilise software and tools to manipulate and analyse immunological data

• Apply appropriate bioinformatics methodologies to their own research

• To combine different types of data (eg genomic and structural) to gain further immunological insights