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Targeted Next-Generation Sequencing Can Help To Diagnose Primary Immune Deficiency Disorders
Next-generation sequencing can allow affordable testing of multiple genes, enabling earlier and more accurate diagnosis for patients with primary immunodeficiency disorders.
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New Biomarker Discovery Could Help Personalize Breast Cancer Treatment
Researchers from the University of Southampton have identified specific structures surrounding breast tumors in overweight cancer patients that may limit their response to therapy.
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Diagnostic Marker Predicts Successful Egg Cell Development
Studying how X chromosomes are inactivated and reactivated during egg cell development could predict successful egg development and help generate human egg cells in the lab.
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Device Could Revolutionize Allergy Diagnosis
A microfluidic device that isolates basophils, the white blood cells that activate inflammation in response to allergens, could be used to design better food allergy tests.
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Blood Test Predicts Response to Immunotherapy
Measuring the total mutations in the DNA of cancer cells from circulating tumor DNA found in the blood can predict how a non-small cell lung cancer patient will respond to immunotherapy.
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New Process Revolutionizes Microfluidic Fabrication
A new process using light-sensitive polymers and micro-LEDs to make devices with microfluidic channels has been developed and is capable of small biomolecule separation.
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Gene Mutation Predisposes Individuals to Severe Staphylococcus Infections
Staphylococcus aureus infections can be highly unpredictable – some cause a slight rash, whereas others can lead to deadly complications – and researchers have identified a genetic mutation that could be the cause of these differences.
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Dozens of Genomic Variations May Drive COVID-19 Clinical Outcomes
A new study identifies dozens of genomic variations that may drive hard-to-predict differences in COVID-19 clinical outcomes. According to the work, genomic variants in four genes that are critical to SARS-CoV-2 infection, including the ACE2 gene, were targets of natural selection and associated with health conditions seen in COVID-19 patients.
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Wearable Gas Sensors Could Improve Environmental and Health Monitoring
New flexible, porous and highly sensitive nitrogen dioxide sensors that can be applied to skin and clothing have potential applications in health care, environmental health monitoring and military use, according to researchers.
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Imaging Approach Helps To Detect Lung Cancer Earlier
Researchers have discovered a way to identify lung cancer at the cellular level in real-time during a biopsy procedure.
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