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CRISPR Gene-Editing Identifies Human Genes Important for HIV Infection
Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).
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New Measure Assesses the Severity of Delirium
Delirium is a serious change in brain function that affects up to 64 percent of older medical patients. While there are more than 30 instruments currently available for identifying delirium in patients, few exist to assess its severity. A new measure changes that.
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Why Immunodeficiency Affects Only One Identical Twin
Common variable immunodeficiency has been categorized at single-cell resolution, revealing that differences in the epigenome and immune cell-cell signaling can cause one identical twin to experience the disease but not the other.
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Increase Sees Half of Older Adults Die With Dementia Diagnosis
A study has shown that nearly half of all older adults now die with a diagnosis of dementia listed on their medical record, up 36% from two decades ago.
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Novel Risk Factors for Arrhythmia Uncovered
A new study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.
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10-Second Videos Predict Blood Cancer Relapse
In a new study, 10-second videos of white blood cell motion in the skin’s microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.
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Why Women's Health Research Needs To Move on From "Bikini Medicine"
A new study has found that women’s health research remains disproportionately focused on the reproductive years - particularly on pregnancy – with few articles on the major causes of illness and death in women.
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“Perfect Storm” of Genetic Mutations Underlie Rare Brain Malformations
A series of genetic mutations have been identified as risk factors for the development of rare brain blood vessel malformations that increase the risk of strokes and seizures.
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Novel COVID-19 Sensor Enables Fast and Accurate Testing
A COVID-19 sensor could revolutionize virus testing by adding accuracy and speed to a process that frustrated many during the pandemic.
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Liquid Biopsy Could Enable Earlier Detection of Metastatic Breast Cancer
Liquid biopsy performed on serum samples taken from breast cancer patients can provide increasingly accurate information on cancer progression and enable earlier detection of cancer recurrence.
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