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Spinal Fluid Biomarkers Detect Neurodegeneration
Alzheimer's disease and other forms of neurodegeneration can currently only be confirmed by autopsy. Researchers say identification may be possible using a combination of biomarkers from the cerebrospinal fluid of living patients.
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Blood Biomarkers Could Help Diagnose Long COVID
Markers in our blood could help identify individuals who have been infected by SARS-CoV-2 several months after infection even if the individual had mild symptoms or showed no symptoms at all.
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COVID-19 Antibodies Persist at Least Nine Months After Infection
Researchers tested 85% of an entire Italian town and found that antibody levels remain high nine months after SARS-CoV-2 infection, whether symptomatic or asymptomatic.
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Study Reveals Even Transient Chromosomal Mistakes Can Initiate Cancer
The findings could be especially relevant to cancer patients undergoing anti-cancer therapy, particularly those being treated with aneugens.
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Test Quantifies Antibodies Against SARS-CoV-2 Rapidly
Scientists have developed a rapid, highly accurate test to detect antibodies against SARS-CoV-2's spike protein within human serum.
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CEA Is Not a Clinically Relevant Biomarker in Anal Cancer
Researchers say that despite patterns of abnormally high CEA in patients with squamous cell carcinoma of the anal canal (SCCA), CEA is not associated with survival outcomes in SCCA, and is not a clinically relevant biomarker in this disease.
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Testing Blood Levels of ACE2 Species Could Help To Monitor SARS-CoV-2 Infection
A blood test that quantifies the protein ACE2, the cellular protein which allows entry of the virus into cells, as well as ACE2 fragments, produced as a result of interaction with the virus, could be an effective method for monitoring SARS-CoV-2 infection.
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Taking Proteomics to Another Level
Proteomics produces enormous amounts of data, which can be very complex to analyze and interpret. The free software platform MaxQuant has proven to be invaluable for data analysis of shotgun proteomics over the past decade. Now, scientists present version 2.0. It provides an improved computational workflow for data-independent acquisition proteomics, called MaxDIA.
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Tooth Loss Linked to Dementia Risk
Tooth loss is a risk factor for cognitive impairment and dementia—and with each tooth lost, the risk of cognitive decline grows, according to a new analysis.
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Novel Screening Approach Improves Diagnosis of Newborn Metabolic Disorders
Researchers have found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when compared to the traditional metabolic screening approach.
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