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A Step Closer to a Skin Swab Test for Parkinson's
Scientists have developed a technique to identify Parkinson's by analyzing compounds found in sebum – an oily substance that coats the skin. The findings could pave the way for the production of a new test to diagnose the degenerative condition through a skin swab.
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Using Whole Genome Sequencing To Guide Blood Cancer Treatment
A new study shows that whole genome sequencing is often more accurate than conventional genetic tests and could help determine the treatment for blood cancers such as acute myeloid leukemia and myelodysplastic syndrome.
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B.1.1.7 COVID-19 Variant Associated With a Significantly Higher Mortality Rate
A study has shown that a SARS-CoV-2 variant, B.1.1.7, is associated with a significantly higher mortality rate compared to previously circulating strains.
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Getting Polygenic Risk Scores Into the Clinic
Polygenic risk scores represent a new approach for assessing a person's inherited risk for certain diseases such as Type 2 diabetes or coronary heart disease. A set of new guidelines for reporting polygenic risk scores in a consistent way, and the launch of an open database for these scores could make the data more useful in clinical care.
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New Test Detects Pre-Dementia Brain Changes
The rate of dementia is increasing worldwide and early detection is critical for treatment, meaning effective screening methods for dementia are a high research priority. Researchers have developed a new computerized cognitive test, which they found to be effective in screening for both dementia and mild cognitive impairment (MCI) in minutes.
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Nanobody-Based Test Detects SARS-CoV-2 in Less Than 10 Minutes
A team of French researchers has developed a simple and highly sensitive prototype test that can detect SARS-CoV-2 in less than 10 minutes.
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Genomic Profiling Tracks the Global Spread of Disease
Scientists in 18 countries have used genome sequencing technology to track the the global spread and exchange of Streptococcus equi, which causes the disease strangles, in the largest ever study of its kind.
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Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
The analysis of immune cells infiltrating cerebrospinal fluid enables the characterization of the tumor microenvironment in brain metastases. Findings confirm that these cells could act as novel and non-invasive biomarkers to predict patient responsiveness to immune-based therapies.
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Low-Cost Method Rapidly Detects SARS-CoV-2 Infection
Researchers have developed improved protocols for the detection of SARS-CoV-2. The method can detect a positive sample in a pool with 25 uninfected samples in less than one hour.
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