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CRISPR Hunts Down Cause of Rare Medical Condition content piece image
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CRISPR Hunts Down Cause of Rare Medical Condition

Virginia Tech scientists with the Fralin Biomedical Research Institute at VTC have manipulated genes to link an undiagnosed human disease with a rare mutation in the PHETA1 gene.
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Scaling Up CRISPR-based Diagnostics

Researchers have developed a new technology that flexibly scales up CRISPR-based molecular diagnostics, using microfluidics chips that can run thousands of tests simultaneously.
Protein Mystery of Three Brain Diseases Unraveled content piece image
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Protein Mystery of Three Brain Diseases Unraveled

The accumulation of one particular protein in the brain is at the basis of three very different age-related conditions. Until recently, nobody understood how this was possible. Research by the Laboratory for Neurobiology and Gene Therapy now reveals that the shape of the protein determines the clinical picture.
Test Detects Antibodies Against SARS-CoV-2 in Only 10 Minutes content piece image
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Test Detects Antibodies Against SARS-CoV-2 in Only 10 Minutes

A proof-of-concept study describes a quick, sensitive test for antibodies against the coronavirus in human blood. The test could help doctors track a person’s exposure to the disease, as well as confirm suspected COVID-19 cases that tested negative by other methods.
NIH Mobilizes National Innovation Initiative for COVID-19 Diagnostics content piece image
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NIH Mobilizes National Innovation Initiative for COVID-19 Diagnostics

A new initiative from NIH aims to speed delivery of accurate, easy-to-use, scalable COVID-19 tests to all Americans.
Ultra-precision Nano-sensor Could Detect Iron Disorders content piece image
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Ultra-precision Nano-sensor Could Detect Iron Disorders

Researchers have developed a hypersensitive nano-sensor to detect harmful "free" iron disorders, which could lead to earlier, more accurate diagnosis.
Sample Pooling Can Massively Increase Coronavirus Testing Capacity content piece image
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Sample Pooling Can Massively Increase Coronavirus Testing Capacity

A team from Saarland University has adapted and tested a method of sample pooling for use in coronavirus diagnostics, which could help to meet the high demand for testing of asymptomatic individuals.

Multicancer Blood Test Could Enable Earlier Detection of Cancer content piece image
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Multicancer Blood Test Could Enable Earlier Detection of Cancer

Results from a first-of-its-kind study of a multicancer blood test in more than 9,900 women with no evidence or history of cancer showed the liquid biopsy test safely detected 26 undiagnosed cancers, enabling potentially curative treatment.
Salmonella Food Poisoning Outbreak Tracking Could Be Improved With DNA Test content piece image
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Salmonella Food Poisoning Outbreak Tracking Could Be Improved With DNA Test

Researchers report the development of a sensitive and specific assay to detect different serotypes of Salmonella, paving the way for rapid serotyping directly from specimens.
Wyss-designed Swabs Enter Human Trials for COVID-19 content piece image
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Wyss-designed Swabs Enter Human Trials for COVID-19

New low-cost nasopharyngeal swabs can be manufactured quickly to address the international shortage of swabs for testing and research.
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