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Reduced Fibromyalgia Pain Scores in People Treated for Insulin Resistance
A retrospective review of people with fibromyalgia revealed insights into a possible pathogenic relationship between fibromyalgia and insulin resistance. Those who had undergone treatment with metformin, a medicine used to treat type 2 diabetes, reported dramatic improvements of their pain after treatment.
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Susceptible Cell Types in Hypoxia Identified
Low oxygen levels are a well-known cause of brain injury in premature babies. Until now, the mechanism by which low oxygen hurts the developing human brain has been unclear.
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Single Gene Mutation Tells Story of Novel Immunodeficiency Disease
A new immunodeficiency disease caused by a novel genetic mutation has been identified by researchers.
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Two-step Test Aims to Diagnose Alzheimer's Patients Earlier
Using current techniques, Alzheimer's disease, the most frequent cause of dementia, can only be detected once the typical plaques have formed in the brain. At this point, therapy seems no longer possible. However, the first changes caused by Alzheimer's take place on the protein level up to 20 years earlier. A new two-tier method can help detect the disease at a much earlier stage.
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Biomarker for Chronic Fatigue Syndrome Identified
People suffering from a debilitating and often discounted disease known as chronic fatigue syndrome may soon have something they’ve been seeking for decades: scientific proof of their ailment.
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Genetics Suggest Why Some People Develop Psychosis
A newly identified epigenetic hotspot for schizophrenia and bipolar disorder may give scientists a fresh path forward for devising more effective treatments and biomarker-based screening strategies.
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How Do Some Patients Naturally Control HIV?
Researchers have used a novel approach to identify specific amino acids in the protein structure of HIV that appear critical to the ability of the virus to function and replicate.
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A Model to Decipher the Complexity of Gene Regulation
More than genes themselves, how, where and when they are expressed determine our biological traits – our phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls those? And how does genetic variation affect them?
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When Art Meets Science and Food Coloring, Bioprinting Prospers
A new open-source method for bioprinting represents a breakthrough for the field of regenerative medicine, and its success stems from a special ingredient: food dye.
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Mutation Once Considered “Incompatible With Life” Actually Causes Intellectual Disability
Researchers have discovered a new genetic defect which causes a form of intellectual disability; a finding that will improve screening programmes and help to end a 'diagnostic odyssey' for families across the globe.
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