News

A non-coding microRNA has been identified as a critical brake in the regulation of a rare aggressive liver cancer. MicroRNA-375 is lost in people with the tumor, highlighting a new target for therapy development.

A team of chemists have examined 456 variations of one class of molecule, lipids, which are vital to cell membrane structure, regulate cell activities and store energy.

Aging promotes lung function decline and increases susceptibility to diseases of the respiratory tract. In order to understand these effects in detail, researchers have analyzed the aging process in the lung at single-cell level, using AI approaches.

A single misbehaving protein – called TDP-43 – is behind 97 percent of amyotrophic lateral sclerosis (ALS) cases and 45 percent of frontotemporal dementia diagnoses. It also is found in 80 percent of chronic traumatic encephalopathy and 60 percent of Alzheimer’s disease cases. Now, researchers have found a way to trap TDP-43 so it doesn’t form toxic clumps that can cause neurodegeneration.

This week, Danaher announced a definitive agreement to purchase General Electric's Biopharma business for a cash purchase price of $21.4 billion. Factoring tax benefits from the structure of the deal, the net purchase price is about $20 billion.

New evidence suggests that Chikungunya virus arrived in Brazil at least one year earlier than it was detected by public health surveillance systems.

Scientists are using sophisticated computational methods to investigate how genetic variation in non-coding DNA can increase a person's susceptibility to certain diseases, such as diabetes and cancer.

Mayo Clinic researchers have identified a gene called "UCP-1" that may predict the development of pancreatic cancer in people with Type 2 diabetes.

The molecular mechanisms behind a newly discovered rare skeletal disease have been described, in which small RNA molecules play a role that has never before been observed in a congenital human disease. The results are important for affected patients but can also help scientists to understand other rare diagnoses.

Scientists have discovered a new protein "switch" that could stop the progression of blood-poisoning, or sepsis, and increase the chances of surviving the life-threatening disease.