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De-escalation of treatment strategies aims to minimize toxicity while maintaining efficacy.

The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and quick action are tied to better outcomes. Now, a new technique to analyze proteins expressed on cancer cells shows promise in more rapidly detecting these cell types.

A new form of synthetic DNA expands the information density of the genetic code, that likely preserves its capability for supporting life, according to a new study. By expanding the genetic alphabet from four letters to eight, researchers demonstrate the ability to double the information density in DNA.

The discovery will help doctors identify the small number of women at most risk who require intervention to prevent stillbirth. This will allow the majority of women with intrahepatic cholestasis of pregnancy who are at a low risk to carry on their pregnancy normally.

The RAPTER platform was able to detect changes in luteinizing hormone pulse patterns in patients with reproductive disorders, and distinguish between different patient cohorts. Unlike current methods, the test is low-cost and can provide results instantly.

A team of biologists, physicists and mathematical modellers in Cambridge have studied the genetic activity of over 100,000 embryonic cells to establish the molecular blueprint of mouse early embryo development.

The George Institute for Global Health at the University of Oxford examined rates and management of diabetes, high cholesterol, high blood pressure, body mass index (BMI) and smoking and found that while there had been some improvements, women were now more likely to be obese and men less likely to have their blood pressure and diabetes under control.

PET scanning has shown that 12 people with documented post-treatment Lyme disease syndrome all show elevation of a chemical marker of widespread brain inflammation, compared with 19 healthy controls.

Birch pollen allergic rhinitis is the most common chronic disorder in the Northern part of the globe, and it attributes to significant morbidity and economic burden. According to a new study, pollen allergen immunotherapy has favorable effects on the molecular events and microbiome profile in the nasal membrane.

A new protocol could help ER physicians to rule out life-threatening bacterial infections among infants up to 2 months of age who have fevers, potentially eliminating the need for unnecessary treatments.