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One Year Later: CRISPR Success in Duchenne Muscular Dystrophy Model
Researchers have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD) -- for more than a year in mice, despite observed immune responses and alternative gene editing outcomes.
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Rare Brain Disease Could Hold Clues for Common Disorders
Researchers have clarified, for the first time, the mechanism behind a very rare brain disorder called MICPCH syndrome in animal models. Information gleaned from this study could also inform research into other, more common neurological disorders such as intellectual disability, epilepsy, and autism.
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Neuromelanin-sensitive MRI a Potential Biomarker for Psychosis
Researchers have shown that a type of magnetic resonance imaging - called neuromelanin-sensitive MRI (NM-MRI) - is a potential biomarker for psychosis.
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100,000-person Study Investigates Association Between Antiepileptic Drugs and Dementia
A study has investigated the hypothetical association between antiepilipetic drug use and dementia risk in 101,150 individuals receiving treatment from more than 1,400 physicians in Germany.
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Selfie Diagnosis With New Phone Camera Tool
Researchers from Florida Atlantic University’s College of Engineering and Computer Science have developed a novel cell phone imaging algorithm that enables analysis of assays typically evaluated via spectroscopy, a highly sophisticated and powerful device used in scientific research.
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AI Predicts Survival of Ovarian Cancer Patients
New machine learning software can forecast the survival rates and response to treatments of patients with ovarian cancer.
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A Fine Balance Between Excitation and Inhibition
Researchers have clarified, for the first time, the mechanism behind a very rare brain disorder called MICPCH (microcephaly, disproportionate pontine and cerebellar hypoplasia) syndrome in animal models.
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Blood Gene Expression Markers Predictive of Pain
A breakthrough test to measure pain in patients could help stem the tide of the opioid crisis in Indiana, and throughout the rest of the nation.
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Fourth Gene Linked to Common Childhood Leukemia
Scientists have identified genetic variations in a fourth gene that are associated with an increased risk of acute lymphoblastic leukemia (ALL) in Hispanic children.
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Micro-CT Captures Lung Cancer Biomarkers
Micro-computed tomography correlates with endpoint histology and was able to detect pre-malignant tumours in mice bearing lung lesions.
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