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A plastic model of a kidney held in a person's hand.
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Imaging Mass Cytometry Provides Insights on Proliferative Lupus Nephritis

A powerful imaging mass cytometry technique has been used for the first time to examine the kidneys of people with lupus, which could help identify drug targets and novel disease markers.
Someone pouring out mouth wash from a bottle.
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A Simple Mouth Rinse Could Help Predict Early Heart Disease Risk

Scientists studying the inflammation that precedes periodontitis have found that higher inflammation, is linked to less healthy arteries and a potentially higher risk of cardiovascular disease even in young, apparently healthy people.
Fluorescent imaging of TDP-43.
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Neurological Spreading Patterns of Disease-Causing Protein TDP-43 Identified

Our movements are controlled by multiple neural pathways that connect the brain and spinal cord. However, this flow of neural information is compromised in amyotrophic lateral sclerosis.
flashing neurons.
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Rapid Genome Sequencing Provided a Diagnosis for 43% of Infants With Unexplained Epilepsy

Epilepsy in infants ranges in severity and can leave caregivers with questions about their child’s health. While genetic testing to help determine the cause of epilepsy is possible, comprehensive testing does not always happen routinely.
An individual with a cartoon intestine on their abdomen.
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Race-Linked Microbiome Changes Detected in Babies

In the United States (US), the composition of the adult gut microbiome has been found to correlate with race and ethnicity, despite there being no genetic or biological reason for this.
Blood is extracted from a person's arm.
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Breakthrough in Brain Rejuvenation Identifies Anti-Aging Plasma Factor

Researchers have long known that the anti-aging hormone klotho, infusions of blood from younger animals and exercise can boost the brain function of aging mice. The underlying mechanism behind these changes has remained elusive until now.
An individual standing in white underwear with cartoon intestines drawn on their abdomen.
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Engineered Probiotics That Can Sense and Report Bowel Inflammation

Trust your gut? Your doctor likely will, too. Probiotics engineered to sense and report signs of bowel inflammation could deliver firsthand knowledge of your system’s inner workings.
A strand of RNA spirals across the image.
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Versatile Technology for Targeted Long-Read RNA Sequencing Developed

A newly developed, versatile and low-cost long-read RNA sequencing tool could accelerate the discovery of new diagnostics and treatments.
A pregnant woman holding her belly.
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Risk of Preterm Birth Is Increased in Mothers With Poor Mental Health

New research has found that women who had at least 1 contact with mental health services in the 7 years prior to their pregnancy were at increased risk of preterm birth.
Four diagnostic test tubes lying on a blue surface.
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Noninvasive Test May Enable Earlier Diagnosis of Bladder Cancer

A new tool that detects a biomarker for bladder cancer – aberrant PENK methylation – has shown promise in detecting cancer earlier.
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