Developing a Breathalyzer-Type Low Blood Sugar Warning Device For Diabetes
News Sep 23, 2015
“Existing technology tracks current blood sugar levels, but it doesn’t alert the patient to an upcoming hypoglycemic episode,” said principal investigator Kody Varahramyan, senior aide to the chancellor and professor of electrical and computer engineering.
Hypoglycemia can be dangerous if it remains undetected. Children and the elderly with Type 1 diabetes are especially prone to sudden drops in blood sugar.
The three-year grant will fund research to:
• Identify the signature odorants that are produced in human breath by specific volatile organic compounds created by the metabolic processes that lead to hypoglycemia, or low blood sugar.
• Develop a nanosensor array to detect those odorants.
• Incorporate the nanosensor array into a portable smart device that transmits health information to the diabetic, caregivers and family members.
“Researchers will identify the signature odorants, which are unknown to the medical community, using breath samples collected from patients,” said Mangilal Agarwal, a co-principal investigator. Agarwal directs the Integrated Nanosystems Development Institute and is associate director of research development in the Office of the Vice Chancellor for Research.
The odorants will be verified with diabetes alert dogs that recognize the onset of hypoglycemia from those odorants. Patients would blow into the small device, whose sensor system would then communicate the patient’s hypoglycemic status, along with tracking information that provides a historical summary.
The research is expected to improve health-monitoring options for people with diabetes, decrease health care costs and improve lifestyles for diabetics.
The grant is part of an effort by the federal government to accelerate the development and use of innovative approaches that would support the transformation of health care from reactive and hospital-centered to preventive, proactive, evidence-based and person-centered, focused on well-being rather than disease.
The project will provide interdisciplinary research experiences to graduate and undergraduate students. In addition, this project will support participation of underrepresented groups and educational outreach programs for K-12 students and teachers across Indiana and the U.S.
“This research is particularly well-suited to an institution like IUPUI, with its focus on health and life sciences, and its ability to marshal experts from across disciplines, including engineering, science, medicine and informatics and computing,” Agarwal said.
Cancer Cells’ Energy Source Blocked by Natural CompoundNews
Researchers have not only untangled an unusual wiring system that cancer cells use for carbohydrate metabolism, but also identified a natural compound that appears to selectively shut down this system in laboratory studies.READ MORE
Methane Hydrate Formation Studied Using Novel MicroreactorNews
Researchers at the NYU Tandon School of Engineering are using a novel means of studying how methane and water form methane hydrate that allows them to examine discrete steps in the process faster and more efficiently.READ MORE
Machine Learning to Increase the Pace of Brain Imaging AnalysisNews
New approach could allow doctors or researchers to quickly identify the data they need, and then rapidly fill in the fine details, making the process faster and more accurate.READ MORE
Comments | 0 ADD COMMENT
13th Edition of International Conference on Pediatric Gastroenterology
Aug 02 - Aug 04, 2018