Horizon Receives the Queen’s Award for Enterprise in International Trade
News Apr 23, 2012
Horizon Discovery (Horizon) has announced that it has won the Queen’s Award 2012 for Enterprise, in the International Trade category.
The prestigious award is in recognition of Horizon Discovery’s outstanding achievement in export growth, having shown overall growth exceeding 360% over the three year period assessed.
Founded in 2007 and based in Cambridge, UK, Horizon has become one of the fastest growing biotechnology companies in Europe.
Expanding over 100% in each year of trading, it now has 70 FTE’s working out of its research facility in Cambridge.
This growth has been built upon an international customer base that includes over 100 academic research organizations and 100 biotechnology, diagnostic and pharmaceutical companies, using a direct selling and partnership strategy.
Greater than 90% of Horizon Discovery sales are currently made into markets outside of the UK, including the USA, Australia, New Zealand, Japan and Singapore.
Of the European market, Germany, Switzerland and Austria are Horizon’s primary sources of trade.
Underpinning Horizon’s global success is the Company’s proprietary technology, GENESIS™, which is the world’s most precise genome editing technology.
Using GENESIS, Horizon is able to alter any endogenous gene sequence of a human or mammalian cell-line quickly, reliably and without introducing unwanted and confounding genotypes and/or phenotypes.
Horizon has harnessed GENESIS to create over 400 X-MAN™ cell lines, the world’s first source of genetically-defined and patient-relevant human cell lines, accurately modeling the disease-causing mutations found in cancer patients.
These ‘patients-in-a-test-tube’ are being used by academic and industry leaders to identify the effect of individual genetic mutations on drug activity, patient responsiveness, and resistance, leading to the successful prediction of which patient sub-groups will respond to currently-available and future drug treatments.
This enables the design of shorter, more focused, and less expensive clinical trials, ultimately providing the tools to identify the ‘right drugs’ for the ‘right patients’ based upon the unique genetic mutations that define their disease.
GENESIS™ and X-MAN™ derived products and services are also finding wide industrial application in bio-pharmaceutical process optimization, clinical diagnostic development, and the provision of reference standards for genomic based clinical research platforms.
“Horizon has worked hard to assemble a team of first class executives, capable of addressing the wide array of commercial opportunities available to the business. Our ability to leverage our technology, product and service base to deliver a combination of large multi-national contracts, strategic alliances, IP assets, spinouts, and direct sales, as well as our successful Centres of Excellence programme, has contributed to our rapid growth over the past years, of which I am very proud,” commented Dr Darrin M Disley, CEO, Horizon.
Dr Disley continued, “Over the coming years we expect further growth in the company’s international customer base which will drive another year of 100% growth in 2012 and greater than 50% for many years to come.”
Mechanism Controlling Multiple Sclerosis Risk IdentifiedNews
Researchers at Karolinska Institutet have now discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through so-called epigenetic regulation. They also found a protective genetic variant that reduces the risk for MS through the same mechanism.
Synthetic DNA Shuffling Enzyme Outpaces Natural CounterpartNews
A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. Researchers say their lipid-scrambling DNA enzyme is the first in its class to outperform naturally occurring enzymes – and does so by three orders of magnitudeREAD MORE
Antarctic Worm and Machine Learning Help Identify Cerebral Palsy EarlierNews
A research team has released a study in the peer-reviewed journal BMC Bioinformatics showing that DNA methylation patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients. The technique which makes use of machine learning, data science and even analysis of Antarctic worms, raises hopes for earlier targeted CP therapies.