MDRNA, Inc. Issued Patent for the Use of Nucleic Acids to Treat Cancer
News Jan 27, 2010
MDRNA, Inc. has announced that the State Intellectual Property Office of the People's Republic of China (PRC) has issued a Notification of Granting Patent Rights for PRC 200480018784 which includes the use of nucleic acids.
The patent describes modulation of claudins, which are proteins implicated in tumor progression and metastasis.
"China's pharmaceutical markets are growing nearly 20% a year," said J. Michael French, President and CEO of MDRNA. "China has seen significant expansion in both the pharmaceutical and biotech sectors, which provides an ideal environment for our ongoing efforts to seek international R&D collaborations and investment opportunities. With this patent and our recent allowance of a patent covering RNAi-based modulation of JAM-1 for the treatment of cancer we continue to extend our oncology patent estate worldwide."
Mechanism Controlling Multiple Sclerosis Risk IdentifiedNews
Researchers at Karolinska Institutet have now discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through so-called epigenetic regulation. They also found a protective genetic variant that reduces the risk for MS through the same mechanism.
Synthetic DNA Shuffling Enzyme Outpaces Natural CounterpartNews
A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. Researchers say their lipid-scrambling DNA enzyme is the first in its class to outperform naturally occurring enzymes – and does so by three orders of magnitudeREAD MORE
Antarctic Worm and Machine Learning Help Identify Cerebral Palsy EarlierNews
A research team has released a study in the peer-reviewed journal BMC Bioinformatics showing that DNA methylation patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients. The technique which makes use of machine learning, data science and even analysis of Antarctic worms, raises hopes for earlier targeted CP therapies.