To continue reading this article, sign up for FREE to
Membership is FREE
and provides you with
instant access
to email newsletters, digital publications, our full content catalogue & more...
MicroRNAs: Their Discovery, Biogenesis, Function and Potential Use as Biomarkers in Non-Invasive Prenatal Diagnostics
Abstract
MiRNAs are a widespread class of small non-coding RNAs that have the ability to silence gene expression through sequence complementarity to their targets.
The regulation of expression and processing of miRNAs, and the mechanisms through which miRNAs locate their correct targets are not yet fully understood. MiRNAs are involved in a multitude of developmental and pathological processes leading to an explosion of research in disparate subject areas. In this review we draw attention to placentally expressed miRNAs that can be detected in the maternal plasma; and we discuss their potential use as biomarkers in non-invasive prenatal diagnostics.
The article is published online in the International Journal of Molecular Epidemiology and Genetics and is free to access.
Add Technology Networks as a preferred Google source to see more of our trusted coverage.
