Organoid Profiling Personalizes Treatments For Pancreatic Cancer

News   Jun 01, 2018 | Original story from Cold Spring Harbor Laboratory

Organoid Profiling Personalizes Treatments For Pancreatic Cancer

This image shows pancreatic cancer cells (nuclei in blue) growing as a sphere encased in membranes (red). Credit: National Cancer Institute \ USC Norris Comprehensive Cancer Center (Min Yu, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC)



Cryo-EM Reveals Interaction Between Major Drug Targets


For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects for conditions ranging from migraine to cancer.


New Ovarian Cancer Target


Researchers have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium deficiency and kidney diseases, may increase the likelihood of surviving ovarian cancer. This new study opens a potential avenue for treating ovarian cancer. Since Calcitriol is an FDA-approved drug, no additional research is needed before the drug can advance to human clinical trials for ovarian cancer.


How Stem Cells Move


Scientists from Newcastle University have shown that human embryonic stem cells move by travelling back and forth in a line, much like ants moving along their trails.



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