Ready-to-Use Tagged cDNA Clones
News Jun 01, 2015
The TrueORF product line is a new generation of cDNA clone products that enables expression of the encoded transcript as a tagged protein. This facilitates multiple downstream applications that utilize an anti-tag antibody (Myc-DDK or GFP) including protein detection, protein purification, subcellular localization, and others.
TrueORFs not only provide an instant solution for tagged protein expression but also offer the flexibility that they can be shuttled into multiple destination vectors. AMSBIO TrueORF cDNA clones have verified and guaranteed insert sequences and have been rigorously tested for expression of the target proteins and their tags.
AMSBIO is able to offer genome wide coverage from its greater than 33,000 human, 25,000 mouse and 15,000 rat full-length validated cDNA clones. Provided as 10ug transfection-ready plasmids and driven by CMV promoters, TrueORF cDNA clones produce authentic transcripts without PCR artifacts.
Researchers have used a method to develop a new blood marker capable of detecting whether or not a person has Alzheimer’s disease. If the method is approved for clinical use, the researchers hope eventually to see it used as a diagnostic tool in primary healthcare. This autumn, they will start a trial in primary healthcare to test the technique.
A team led by Johns Hopkins Medicine researchers says it has identified two protein biomarkers in urine that may one day be used to better diagnose acute interstitial nephritis, an underdiagnosed but treatable kidney disorder that impairs renal function in the short term and can lead to chronic kidney disease, permanent damage or renal failure if left unchecked.READ MORE