We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Researchers Test Drug Transfer Using Placenta-On-A-Chip

News   Feb 19, 2018 | Original story from University of Pennsylvania

 
Researchers Test Drug Transfer Using Placenta-On-A-Chip

The Huh lab's placenta-on-a-chip features two microfluidic channels that represent the maternal and fetal circulatory systems, and a membrane with living cells from the placental barrier that separates the two. There are few good options for testing how pharmaceuticals and other supplements might cross the placental barrier during pregnancy. Simulating that barrier on a chip, using human cells, is an alternative to inconclusive animal models, or using placental tissue donated after birth, which have a limited lifespan and require complicated experimental set-ups. Credit: University of Pennsylvania

 
 
 

RELATED ARTICLES

Bacterial ‘Sleeper Cells’ Evade Antibiotics and Weaken Defence Against Infection

News

These bacteria persister cells stop replicating and can remain in this dormant, ‘sleeper-cell’ state for days, weeks or even months. When antibiotic treatment has been stopped, if some of these bacterial cells spring back to life, they can trigger another infection.

READ MORE

From Fibroblast to Antigen-presenting Dendritic Cell: a Pioneering Approach

News

Direct programming of mouse and human skin cells into antigen-presenting dendritic cells opens up the possibility of developing novel dendritic cell-based immunotherapies against cancer.

READ MORE

Emerging Strategies for Treating Opioid-use Disorder

News

Anti-opioid immunopharmacotherapies (e.g., conjugate vaccines) that sequester drug peripherally, preventing opioids from reaching targeted receptors in the brain, have recently emerged as promising therapeutics.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE