Latest Posters
Poster
Leveraging CI-H Mass Defect Plots for the Identification of Halogenated Organic Contaminants
A number of legacy contaminants and other pesticides, as well as a number of previously unknown compounds were tentatively identified in the pooled sample. Cl-H mass defect plots are a useful tool for filtering through complex data for the identification of halogenated contaminants. This technique functions as a screening tool for the identification of unknowns, and in the future, may be used as a form of fingerprinting to compare samples.
Poster
A Workflow for Comprehensive Analysis of Forensic Samples Using Electron and Chemical Ionization High Resolution Time-of-Flight Mass Spectrometry
EI/CI workflow facilitates confident compound identification. Proper sample preparation is critical for the analysis of complex samples. GC-HRT provides high quality, accurate mass data for:
-Spectral similarity searches (NIST, Wiley, etc.)
-Formula determination (fragment, molecular, and adduct ions)
-Spectral similarity searches (NIST, Wiley, etc.)
-Formula determination (fragment, molecular, and adduct ions)
Poster
Metabolism of Eight Model Pharmaceutical Compounds in Rat and Human HepatoPac Versus Liver Microsomes and Suspension Hepatocyte Platforms
This poster presents our comparative metabolite profiling analysis of eight model pharmaceutical compounds with various biotransformation reactions using a functionally stable model of primary hepatocytes [micropatterned co-cultures (MPCCs)] in parallel with the traditional liver microsomal and suspension hepatocyte systems.
Poster
Developing a digital histopathology platform to support an international diabetes biobank
An online histopathology platform combines tissue samples and online digital histopathology images. We combine detailed online patient data with whole slide images. This allows potential users of the tissue bank material to select the tissue and patient characteristics before entering into a collaborative agreement. The digital histopathology platform also allows different pathology laboratories in Belgium to discuss histopathological slides, and facilitates research collaboration.
Poster
Recent Technical Developments in the Standardized Separation and Measurement of Extracellular Vesicles
We present robust and practical solutions for the standardization of EV isolation and concentration measurement. EV concentration also needs to have a defined size range. With these solutions, significant improvement in the reproducibility and comparability of results between different researchers is possible.
Poster
High Titre BacMam viruses improve transduction efficiency of mammalian cells
We present a method for producing high titre BacMam virus vectors for the efficient transduction of mammalian cells.
Poster
Characterization of Proteins and Protein Self Association (Oligomerization) with SEC-MALS
In this poster, a series of proteins and their oligomers were characterized using SEC-MALS with UV and RI detection. The monomer molecular weights are measured and compared with those from column calibration. The molecular weights of their oligomers are also compared with column calibration and the differences explored.
Poster
Performance of a hybrid gamma-optical camera for improved utility in diagnostic imaging
Performance of a hybrid gamma-optical camera for improved utility in diagnostic imaging
Poster
Amino-Coated Metallofullerene Nanoparticles for Glioblastoma Mutiforme Tumor Detection
We report the preparation of a new functionalized trimetallic nitride endohedral metallofullerene, with a cage surface consisting of positively charged amino groups, which is expected to bind more efficiently to negatively charged cell phospholipid bi-layer cellular surfaces and will more readily undergo endocytosis. We now report that this Gd-nanoplatform when subsequently conjugated with an IL-13 peptide, (IL-13-Gd3N@C80(OH)x(NH2)y) exhibits enhanced targeting of U-251 GBM cell lines.
Poster
High Throughput Screening in the European Lead Factory
This paper describes workflows that have been implemented at the screening centre of the European Lead Factory and presents screening statistics on the first 18 months of operation.
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